Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
5-ethoxycarbonyl-2-amino-4-(2-nitrophenyl)-3-cyano-6-methyl-4h-pyran | 6-Amino-5-cyano-2-methyl-4-(2-nitro-phenyl)-4H-pyran-3-carboxylic acid ethyl est | 72568-53-7; |
AG-205/33677015 | AKOS000558197 | AKOS021988145 |
MCULE-1829228796 | Oprea1_672599 | RSCBB000230 |
SR-01000423362 | SR-01000423362-1 | ST003353 |
STK725700 | ethyl 6-amino-5-cyano-2-methyl-4-(2-nitrophenyl)-4H-pyran-3-carboxylate | ethyl 6-amino-5-cyano-4-{2-nitrophenyl}-2-methyl-4H-pyran-3-carboxylate |
CAS Number | 72568-53-7 |
PubChem Compound | 2831068 |