Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
AKOS001033890 | Bis(2-phenylvinyl)phosphinic acid | HMS1578G16 |
Oprea1_843021 | SCHEMBL9815253 | ST50979340; |
ZINC235106 | bis((1E)-2-phenylvinyl)phosphinic acid |
CAS Number | 4970-39-2 |
PubChem Compound | 787101 |