MITOTOX

Compound

D1230 | 2,5-Diaminoterephthalic acid

Properties

Molecular Formula	C8H8N2O4
Molecular Weight	196.16
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
S,N-GLYCEROPHOSPHATE SHUTTLE	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect		162

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
Glycerol-3-phosphate dehydrogenase, mitochondrial	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	inhibitor		162

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Warning	Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Warning

Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure

Respiratory tract irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

1,4-Benzenedicarboxylic acid, 2,5-diamino-	2,5-DIAMINOTEREPHTHALICACID	2,5-Diaminoterephthalic acid, >=95% (HPLC);
2,5-diaminobenzene-1,4-dicarboxylic acid	2,5-diaminoterephthalic acid	945-30-2
ACMC-20aobh	ACN-P001076	AKOS000541081
AS-59320	AX8221961	CBDivE_006536
CS-0110720	CTK3G9221	Cambridge id 5180162
DA-16740	DTXSID20355701	FCH835597
FT-0736091	MCULE-2871607641	ML01047
Oprea1_205111	Oprea1_216725	SCHEMBL987442
ST50229678	STK036387	TC-171188
ZINC330106

External IDs

CAS Number	945-30-2
PubChem Compound	816761