Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
412964-20-6 | AG-690/34158016 | AKOS005438000 |
MCULE-7274149162 | N-(1-adamantylcarbonyl)-N'-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)thiourea | N-[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamothioyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide; |
Oprea1_830622 | STK329027 | ZINC4321571 |
CAS Number | 412964-20-6 |
PubChem Compound | 2830758 |