Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
2-(isobutylthio)succinic acid | 2-[(2-methylpropyl)sulfanyl]butanedioic acid | AB00074583-01; |
AKOS001645690 | CBDivE_003448 | CCG-110962 |
Cambridge id 5152843 | MCULE-5025540855 | STK531081 |
PubChem Compound | 2830878 |