Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
AB00075093-01 | AKOS000482987 | AN-329/10003008 |
ARONIS017109 | Cambridge id 5191683 | KS-000049LX |
MCULE-8346367144 | N-{4-[acetyl(methyl)amino]phenyl}-4-biphenylcarboxamide | N-{4-[acetyl(methyl)amino]phenyl}[1,1'-biphenyl]-4-carboxamide; |
N-{4-[acetyl(methyl)amino]phenyl}biphenyl-4-carboxamide | Oprea1_485405 | Oprea1_563850 |
STK089993 | ZINC2472236 |
PubChem Compound | 2054616 |