Compound
D1235 | 3-(2-Chloro-phenyl)-2-(4-(2-oxo-2H-chromen-3-YL)-thiazol-2-YL)-acrylonitrile
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
| (2E)-3-(2-chlorophenyl)-2-[4-(2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile | 3-(2-CHLORO-PHENYL)-2-(4-(2-OXO-2H-CHROMEN-3-YL)-THIAZOL-2-YL)-ACRYLONITRILE | 333769-55-4; |
| AB00075368-01 | AKOS001142783 | C21H11ClN2O2S |
| STK870495 | ZINC3995819 |
| CAS Number | 333769-55-4 |
| PubChem Compound | 5331268 |