Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
5-(2-Nitrobenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione | 5-(2-nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | 5-(2-nitrobenzylidene)thiobarbiturate |
5-[(2-nitrophenyl)methylene]-2-thioxo-1,3-dihydropyrimidine-4,6-dione; | AKOS000671114 | CBDivE_011239 |
CHEMBL4172998 | MCULE-3229844389 | ST50745428 |
STK156800 | ZINC325153 |
PubChem Compound | 813003 |