Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
(2Z)-2-(aminothioxomethyl)-3-(4-bromo(2-thienyl))prop-2-enenitrile | 3-(4-bromo-2-thienyl)-2-cyano-2-propenethioamide; | AB00074978-01 |
AG-690/36878058 | AKOS000668628 | BBV-71547720 |
FCH3278717 | FCH3434446 | ST020711 |
ZINC32223241 |
PubChem Compound | 679235 |