Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
184530-24-3; | AB00075382-01 | AKOS005624562 |
Benzyl [(6-amino-3,5-dicyano-4-ethyl-2-pyridinyl)thio]acetate | CHEMBL1529042 | HMS1578C15 |
HMS2413D04 | MCULE-2017934268 | MLS000106027 |
SMR000102998 | SR-01000198675 | SR-01000198675-1 |
STK837908 | ZINC19337959 | benzyl [(6-amino-3,5-dicyano-4-ethylpyridin-2-yl)sulfanyl]acetate |
CAS Number | 184530-24-3 |
PubChem Compound | 1067782 |