Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
AKOS000520538 | BRD-K46268007-001-01-5 | CBDivE_009693 |
MCULE-3199729684 | N-[2-[(1,3-Diphenyl-1H-pyrazol-5-yl)amino]phenyl]benzamide | N-{2-[(1,3-diphenyl-1H-pyrazol-5-yl)amino]phenyl}benzamide |
N-{2-[(1,3-diphenylpyrazol-5-yl)amino]phenyl}benzamide; | Oprea1_112740 | Oprea1_632011 |
SCHEMBL14132972 | ST50225031 | ZINC2473143 |
PubChem Compound | 2054834 |