Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
2-Butylsulfanyl-6-methyl-9H-1,3,4,9-tetraaza-fluorene | 3-(butylsulfanyl)-8-methyl-5H-[1,2,4]triazino[5,6-b]indole; | AB00075849-01 |
AKOS000362361 | CCG-113068 | Cambridge id 5225633 |
MCULE-2877279180 | STK508872 | ZINC2981613 |
PubChem Compound | 6408685 |