MITOTOX

Compound

D1270 | Thiangazole

Properties

Molecular Formula	C26H29N5O2S3
Molecular Weight	539.7
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
ELECTRON TRANSPORT CHAIN	0.04 nmol/mg		bovine	mitochondria	NADH–Q	decrease	IC50	94

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
NADH:ubiquinone reductase	0.04 nmol/mg		bovine	mitochondria	NADH–Q	inhibitor	IC50	94

Indications Source: SIDER

Synonyms Source: PubChem

(-)-Thiangazole	138667-71-7	4-Oxazolecarboxamide,2-(4,4',4'',5,5',5''-hexahydro-4,4',4''-trimethyl-2''-(2-phenylethenyl)(2,4':2',4''-terthiazol)-4-yl)-N,5-dimethyl-, (4R-(2(2'(2''(E),4''S),4'S),4R*))-
4-Oxazolecarboxamide,2-[4,4',4'',5,5',5''-hexahydro-4,4',4''-trimethyl-2''-(2-phenylethenyl)[2,4':2',4''-terthiazol]-4-yl]-N,5-dimethyl-, [4R-[2[2'[2''(E),4''S],4'S],4R*]]-	N,5-dimethyl-2-[(4R)-4-methyl-2-[(4S)-4-methyl-2-[(4S)-4-methyl-2-[(E)-styryl]-5H-thiazol-4-yl]-5H-thiazol-4-yl]-5H-thiazol-4-yl]oxazole-4-carboxamide	SCHEMBL13342866
Thiangazole	Thiangazole A

External IDs

CAS Number	138667-71-7
PubChem Compound	6451119
ChemSpider	4953604

References