F0101 | Depolarization
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Paraquat | increase | Positive | 67 | ||||||
| Cyclosporin A | 1 μmol/L | 3 minutes | rat | liver mitochondria | Assessment of Mitochondrial Membrane Potential; coincubated with diclofenac | decrease | Positive | p < 0.05 | 6 |
| DPPD | 1 μmol/L | 3 minutes | rat | liver mitochondria | Assessment of Mitochondrial Membrane Potential; coincubated with diclofenac | decrease | Positive | p < 0.05 | 6 |
| Clozapine | Increase | Positive | 307 | ||||||
| Bupivacaine | decrease | Positive | 61 | ||||||
| Lidocaine | Positive | 197 | |||||||