Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|---|
tacrolimus | 1 μM | rat | isolated kidney mitochondria | Oxygen consumption was measured with a Clark‐type electrode | decrease | Positive | 323 | ||
rapamycin | 1 μM | rat | isolated kidney mitochondria | Oxygen consumption was measured with a Clark‐type electrode | decrease | Positive | 323 | ||