F020302 | Generation of isocitrate
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Metformin | 0.5mM | 24 hours | human | MCF10A | Meassurement of isocitrate concentration; compared with MCF10A | affect | Positive | p < 0.05 | 172 |
| Metformin | 0.5mM | 24 hours | human | MCF7 | Meassurement of isocitrate concentration; compared with MCF10A | affect | Positive | p < 0.05 | 172 |