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F020304 | Generation of succinate

GO:0006105 map00020 R-HSA-71403
Function of mitochondria >> TCA >> generation of succinate

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Metformin 5mM 30 minutes mouse; C57BL/6J isolated skeletal muscle mitochondria Meassurement of succinate concentration decrease Positive p < 0.05 172
Metformin 5mM 30 minutes mouse; C57BL/6J isolated skeletal muscle mitochondria Meassurement of succinate concentration decrease Positive p < 0.05 172

T109. succinate