1. |
Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. |
McGill, Mitchell R; Williams, C David; Xie, Yuchao; Ramachandran, Anup; Jaeschke, Hartmut |
Toxicology and Applied Pharmacology |
2012 |
10.1016/j.taap.2012.08.015 |
2. |
Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. |
Raza, Haider; John, Annie; Benedict, Sheela |
European Journal of Pharmacology |
2011 |
10.1016/j.ejphar.2011.06.016 |
3. |
Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. |
Nadanaciva, Sashi; Bernal, Autumn; Aggeler, Robert; Capaldi, Roderick; Will, Yvonne |
Toxicology in Vitro |
2007 |
10.1016/j.tiv.2007.01.011 |
4. |
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. |
Kaufmann, Priska; Török, Michael; Hänni, Anya; Roberts, Paul; Gasser, Rodolfo; Krähenbühl, Stephan |
Hepatology |
2005 |
10.1002/hep.20634 |
5. |
The in vitro and in vivo antitumor effects of clotrimazole on oral squamous cell carcinoma. |
Wang, Juan; Jia, Lihua; Kuang, Zirong; Wu, Tong; Hong, Yun; Chen, Xiaobing; Leung, W Keung; Xia, Juan; Cheng, Bin |
Plos One |
2014 |
10.1371/journal.pone.0098885 |
6. |
Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats. |
Masubuchi, Yasuhiro; Nakayama, Shintaro; Horie, Toshiharu |
Hepatology |
2002 |
10.1053/jhep.2002.31871 |
7. |
Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform. |
Nadanaciva, Sashi; Rana, Payal; Beeson, Gyda C; Chen, Denise; Ferrick, David A; Beeson, Craig C; Will, Yvonne |
Journal of Bioenergetics and Biomembranes |
2012 |
10.1007/s10863-012-9446-z |
8. |
N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. |
Rodriguez, R J; Acosta, D |
Toxicology |
1997 |
10.1016/s0300-483x(96)03560-3 |
9. |
Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis |
Matsubara, |
International Journal of Molecular Medicine |
1905 |
10.3892/ijmm_00000034 |
10. |
Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals. |
McArdle, Joseph J; Sellin, Lawrence C; Coakley, Kathleen M; Potian, Joseph G; Hognason, Kormakur |
Neuropharmacology |
2006 |
10.1016/j.neuropharm.2005.09.011 |
11. |
Generation of free radicals during the reductive metabolism of nilutamide by lung microsomes: possible role in the development of lung lesions in patients treated with this anti-androgen. |
Berger, V; Berson, A; Wolf, C; Chachaty, C; Fau, D; Fromenty, B; Pessayre, D |
Biochemical Pharmacology |
1992 |
10.1016/0006-2952(92)90593-8 |
12. |
The uncoupling effect of the nonsteroidal anti-inflammatory drug nimesulide in liver mitochondria from adjuvant-induced arthritic rats. |
Caparroz-Assef, S M; Salgueiro-Pagadigorria, C L; Bersani-Amado, C A; Bracht, A; Kelmer-Bracht, A M; Ishii-Iwamoto, E L |
Cell Biochemistry and Function |
2001 |
10.1002/cbf.904 |
13. |
Nitrofurantoin inhibition of mouse liver mitochondrial respiration involving NAD-linked substrates |
Lim, Lori O.; Bortell, Rita; Neims, Allen H. |
Toxicology and Applied Pharmacology |
1986 |
10.1016/0041-008X(86)90254-1 |
14. |
Complex I is the major site of mitochondrial superoxide production by paraquat. |
Cochemé, Helena M; Murphy, Michael P |
The Journal of Biological Chemistry |
2008 |
10.1074/jbc.M708597200 |
15. |
Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. |
Dykens, James A; Jamieson, Joseph; Marroquin, Lisa; Nadanaciva, Sashi; Billis, Puja A; Will, Yvonne |
Toxicology and Applied Pharmacology |
2008 |
10.1016/j.taap.2008.08.013 |
16. |
Perhexiline. |
Ashrafian, Houman; Horowitz, John D; Frenneaux, Michael P |
Cardiovascular drug reviews |
1905 |
10.1111/j.1527-3466.2007.00006.x |
17. |
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. |
Lee, Leong; Horowitz, John; Frenneaux, Michael |
European Heart Journal |
2004 |
10.1016/j.ehj.2004.02.018 |
18. |
Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells. |
Barry, W H; Horowitz, J D; Smith, T W |
British Journal of Pharmacology |
1985 |
10.1111/j.1476-5381.1985.tb08830.x |
19. |
Inhibitory effects of some cyclohexylaralkylamines related to perhexiline on sodium influx, binding of [3H]batrachotoxinin A 20-alpha-benzoate and [3H]nitrendipine and on guinea pig left atria contractions. |
Grima, M; Velly, J; Decker, N; Marciniak, G; Schwartz, J |
European Journal of Pharmacology |
1988 |
10.1016/0014-2999(88)90776-5 |
20. |
Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation. |
Kennedy, Jennifer A; Beck-Oldach, Konstanz; McFadden-Lewis, Kate; Murphy, Geraldine A; Wong, Yee W; Zhang, Yi; Horowitz, John D |
European Journal of Pharmacology |
2006 |
10.1016/j.ejphar.2005.11.058 |
21. |
Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain. |
García-Ruiz, Inmaculada; Solís-Muñoz, Pablo; Fernández-Moreira, Daniel; Muñoz-Yagüe, Teresa; Solís-Herruzo, José A |
BMC Biology |
2013 |
10.1186/1741-7007-11-88 |
22. |
Effect of tricyclic drugs on mitochondrial membrane. |
Eto, K; Fukuda, T; Araki, Y; Inoue, B; Ogata, M |
Acta medica Okayama |
1985 |
10.18926/AMO/31500 |
23. |
Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. |
Modica-Napolitano, Josephine S; Lagace, Christopher J; Brennan, William A; Aprille, June R |
Archives of Pharmacal Research |
2003 |
10.1007/bf02980205 |
24. |
2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. |
Grundlingh, Johann; Dargan, Paul I; El-Zanfaly, Marwa; Wood, David M |
Journal of Medical Toxicology |
2011 |
10.1007/s13181-011-0162-6 |
25. |
Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells. |
Zhang, Fanjie; Aft, Rebecca L |
Journal of cancer research and therapeutics |
2009 |
10.4103/0973-1482.55140 |
26. |
Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. |
Ma, Xiuquan; Jin, Mingzhi; Cai, Yu; Xia, Hongguang; Long, Kai; Liu, Junli; Yu, Qiang; Yuan, Junying |
Chemistry & Biology |
2011 |
10.1016/j.chembiol.2011.08.009 |
27. |
The kinetic mechanism by which CCCP (carbonyl cyanide m-chlorophenylhydrazone) transports protons across membranes. |
Kasianowicz, J; Benz, R; McLaughlin, S |
The Journal of Membrane Biology |
1905 |
10.1007/bf01868942 |
28. |
Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors. |
Vickers, Alison E M |
Toxicologic Pathology |
2009 |
10.1177/0192623308329285 |
29. |
Myxothiazol, a new inhibitor of the cytochrome b-c1 segment of the respiratory chain |
Thierbach, Georg; Reichenbach, Hans |
Biochimica et Biophysica Acta (BBA) - Bioenergetics |
1981 |
10.1016/0005-2728(81)90238-3 |
30. |
Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity. |
Morikawa, N; Nakagawa-Hattori, Y; Mizuno, Y |
Journal of Neurochemistry |
1996 |
10.1046/j.1471-4159.1996.66031174.x |