T084 Source: Uniprot
enzymeMitochondrial pyruvate carrier 1
(Brain protein 44-like protein)
Transporter
| Full Name | Mitochondrial pyruvate carrier 1 |
|---|---|
| Protein Names | Mitochondrial pyruvate carrier 1 (Brain protein 44-like protein) |
| Subcellular Location | Mitochondrion inner membrane Multi-pass membrane protein |
| Uniprot Accession | Q9Y5U8 |
| Uniprot Name | MPC1_HUMAN |
| Gene symbol | MPC1 |
| Gene Name | Mitochondrial pyruvate carrier 1 |
| Ensembl | ENSG00000060762 |
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Valproic Acid | 0.5–2 mM | 3min | rat | inverted submitochondrial vesicles (ISMV) from rat liver isolated mitochondria | The rate of the radiolabeled substrate [1-14C]-pyruvate uptake by ISMV was measured in the presence or absence of an inwardly directed proton gradient. | Positive | 279 | |