T409 Source: Uniprot

enzymeCaspase-3 (CASP-3)
Thiol protease Protease Hydrolase
Full Name Caspase-3
Protein Names Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Subcellular Location Cytoplasm
EC numbers 3.4.22.56
Uniprot Accession P42574
Uniprot Name CASP3_HUMAN
Gene symbol CASP3
Gene Name Caspase 3
Ensembl ENSG00000164305

Compound Dose Time Species Model Method Result Positive criterion Reference
Troglitazone 100 ┬ÁM 24hr HepG2 cells Apo-One homogeneous caspase 3 assay kit Positive 330
Niclosamide Positive 294
sertraline Positive 307
Fluoxetine Positive 307