T422 Source: Uniprot
enzymeNAD-dependent protein deacetylase sirtuin-1
(hSIRT1)
Transferase
Developmental protein
| Full Name | NAD-dependent protein deacetylase sirtuin-1 |
|---|---|
| Protein Names | NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] |
| Subcellular Location | Cytoplasm Mitochondrion Nucleus Nucleus, PML body [SirtT1 75 kDa fragment]: Cytoplasm |
| EC numbers | 2.3.1.286; 2.3.1.- |
| Uniprot Accession | Q96EB6 |
| Uniprot Name | SIR1_HUMAN |
| Gene symbol | SIRT1 |
| Gene Name | Sirtuin 1 |
| Ensembl | ENSG00000096717 |
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| resveratrol | Positive | 267 | ||||||