D0183 | H2O2
S
A
D
S02AA06 Hydrogen peroxide
[S02AA] Antiinfectives
[S02A] ANTIINFECTIVES
[S02] OTOLOGICALS
[S] Sensory organs
D11AX25 Hydrogen peroxide
[D11AX] Other dermatologicals
[D11A] OTHER DERMATOLOGICAL PREPARATIONS
[D11] OTHER DERMATOLOGICAL PREPARATIONS
[D] Dermatological drugs
D08AX01 Hydrogen peroxide
[D08AX] Other antiseptics and disinfectants
[D08A] ANTISEPTICS AND DISINFECTANTS
[D08] ANTISEPTICS AND DISINFECTANTS
[D] Dermatological drugs
A01AB02 Hydrogen peroxide
[A01AB] Antiinfectives and antiseptics for local oral treatment
[A01A] STOMATOLOGICAL PREPARATIONS
[A01] STOMATOLOGICAL PREPARATIONS
[A] Alimentary tract and metabolism
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| FRAGMENTATION | 10 μmol/10E7 cells | 4-6hr | C2C12 mouse | muscle myoblasts | detected by either MitoTracker Red staining, or by mERFP transfection | induce | 297 | |
| MEGAMITOCHONDRIA | 0.2mM | 22hr | rimary culture rat hepatocytes, RL-34,COS-1, IAR-20 | induce | 292 | |||
| MITOCHONDRIAL MOTILITY | 50 μM | Time lapse fluorescence microscopy | decrease | 218 | ||||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
H271: May cause fire or explosion strong Oxidizer [Danger Oxidizing liquids Oxidizing solids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] |
P210, P220, P221, P260, P261, P264, P270, P271, P280, P283, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P306+P360, P310, P312, P321, P330, P363, P370+P378, P371+P380+P375, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 2421 companies from 61 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 2 of 2421 companies. For more detailed information, please visit ECHA C&L website Of the 60 notification(s) provided by 2419 of 2421 companies with hazard statement code(s): H271 (91.9%): May cause fire or explosion strong Oxidizer [Danger Oxidizing liquids Oxidizing solids] H302+H332 (19.76%): Harmful if swallowed or if inhaled [Warning Acute toxicity, oral acute toxicity, inhalation] H302 (97.89%): Harmful if swallowed [Warning Acute toxicity, oral] H314 (99.75%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318 (48.41%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H332 (94.87%): Harmful if inhaled [Warning Acute toxicity, inhalation] H335 (42.04%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H412 (16.49%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P210, P220, P221, P260, P261, P264, P270, P271, P273, P280, P283, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P306+P360, P310, P312, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H271: May cause fire or explosion strong Oxidizer [Danger Oxidizing liquids Oxidizing solids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] |
P210, P220, P221, P260, P261, P264, P270, P271, P280, P283, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P306+P360, P310, P312, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
P260, P261, P264, P271, P273, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
  |
Danger |
H271: May cause fire or explosion strong Oxidizer [Danger Oxidizing liquids Oxidizing solids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H351: Suspected of causing cancer [Warning Carcinogenicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P210, P220, P221, P260, P261, P264, P270, P271, P280, P281, P283, P284, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P306+P360, P307+P311, P308+P313, P310, P311, P312, P314, P320, P321, P322, P330, P361, P363, P370+P378, P371+P380+P375, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H271: May cause fire or explosion strong Oxidizer [Danger Oxidizing liquids Oxidizing solids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H313: May be harmful in contact with skin [Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P210, P220, P221, P260, P261, P264, P270, P271, P280, P281, P283, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P306+P360, P307+P311, P308+P313, P310, P311, P312, P314, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | skin | 4060mg/kg (4060mg/kg) | lungs, thorax, or respiration: pulmonary emboli | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(10), Pg. 22, 1977. |
| man | TDLo | parenteral | 5714uL/kg (5.714mL/kg) | Intensive Care Medicine. Vol. 21, Pg. 287, 1995. | |
| women | LDLo | oral | 2626ug/kg (2.626mg/kg) | Sudebno-Meditsinskaya Ekspertiza. Forensic Medical Examination. Vol. 17(1), Pg. 53, 1974. | |
| child | LDLo | oral | 8500mg/kg (8500mg/kg) | Critical Care Medicine. Vol. 20, Pg. 543, 1992. | |
| mouse | LD50 | subcutaneous | 1072mg/kg (1072mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 28, 1983. | |
| rat | LC50 | inhalation | 2gm/m3/4H (2000mg/m3) | lungs, thorax, or respiration: pulmonary emboli | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(10), Pg. 22, 1977. |
| mouse | LD50 | oral | 2gm/kg (2000mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 28, 1983. | |
| rat | LD50 | subcutaneous | 620mg/kg (620mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 28, 1983. | |
| rat | LD50 | oral | 1518mg/kg (1518mg/kg) | behavioral: somnolence (general depressed activity) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 23, Pg. 531, 1976. |
| mouse | LD50 | skin | 12gm/kg (12000mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 28, 1983. | |
| child | LDLo | oral | 12mL/kg (12mL/kg) | American Journal of Forensic Medicine and Pathology. Vol. 15, Pg. 44, 1994. | |
| mouse | LD50 | intraperitoneal | 880mg/kg (880mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 28, 1983. | |
| rat | LD50 | skin | 3gm/kg (3000mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 39, 1999. | |
| pig | LDLo | skin | 2gm/kg (2000mg/kg) | behavioral: convulsions or effect on seizure threshold | U.S. Army, Chemical Corps Medical Laboratories Research Reports. Vol. #75, Pg. 1951, |
| rat | LD50 | oral | 910mg/kg (910mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 39, 1999. | |
| man | LDLo | oral | 1429mg/kg (1429mg/kg) | Sudebno-Meditsinskaya Ekspertiza. Forensic Medical Examination. Vol. 17(1), Pg. 53, 1974. | |
| rabbit | LD50 | intravenous | 15gm/kg (15000mg/kg) | behavioral: convulsions or effect on seizure threshold | U.S. Army, Chemical Corps Medical Laboratories Research Reports. Vol. #75, Pg. 1951, |
| mouse | LCLo | inhalation | 227ppm (227ppm) | Archives of Environmental Health. Vol. 4, Pg. 327, 1962. | |
| rabbit | LD50 | oral | 820mg/kg (820mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 39, 1999. | |
| women | TDLo | oral | 9460mg/kg (9460mg/kg) | Annals of Emergency Medicine. Vol. 18, Pg. 778, 1989. | |
| child | LDLo | oral | 9mL/kg (9mL/kg) | American Journal of Forensic Medicine and Pathology. Vol. 15, Pg. 44, 1994. | |
| women | TDLo | oral | 1200mg/kg (1200mg/kg) | Annals of Emergency Medicine. Vol. 21, Pg. 1391, 1992. | |
| rat | LD50 | oral | 376mg/kg (376mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 39, 1999. | |
| rabbit | LDLo | skin | 500mg/kg (500mg/kg) | behavioral: convulsions or effect on seizure threshold | U.S. Army, Chemical Corps Medical Laboratories Research Reports. Vol. #75, Pg. 1951, |
| mouse | LD50 | intravenous | > 50gm/kg (50000mg/kg) | Hunan Yixueyuan Xuebao. Journal of Hunan Medical College. Vol. 5, Pg. 39, 1980. | |
| 30 %Hydrogen peroxide(aq) | 7722-84-1 | 8007-30-5 |
| ACMC-20akqy | AKOS015856794 | Accel Concentrate |
| Adeka Super EL | Albone | Albone 35 |
| Albone 35CG | Albone 50 | Albone 50CG |
| Albone 70 | Albone 70CG | Albone DS |
| Anti-Keim 50 | Asepticper | Astri-UC |
| BBX060AN9V | Baquashock | C00027 |
| CCRIS 1060 | CHEBI:16240 | CHEMBL71595 |
| CIX | CTK2H7501 | Caswell No. 486AAA |
| Clarigel Gold | Crestal Whitestrips | Crystacide |
| D00008 | DB11091 | DTXSID2020715 |
| Dentasept | Deslime LP | Dihydrogen dioxide |
| EC 231-765-0 | EINECS 231-765-0 | EPA Pesticide Chemical Code 000595 |
| Elawox | Eskata | FT-0627133 |
| H2O2 | HOOH | HSDB 547 |
| HTP [peroxide] | HYDROGEN PEROXIDE | HYDROGEN-PEROXIDE |
| High Test Peroxide | Hioxy | Hioxyl |
| Hipox | Hybrite | Hydrogen Peroxide Solution, 30% (w/w), puriss. p.a., reag. ISO, reag. Ph. Eur. |
| Hydrogen Peroxide [Topical Solution] | Hydrogen Peroxide, 50% | Hydrogen dioxide |
| Hydrogen dioxide solution | Hydrogen peroxide (8CI) | Hydrogen peroxide (> 52% conc.) |
| Hydrogen peroxide (H2O2) | Hydrogen peroxide (H2O2) (9CI) | Hydrogen peroxide (USP) |
| Hydrogen peroxide (conc > 52%) | Hydrogen peroxide (conc >52%) | Hydrogen peroxide 35% |
| Hydrogen peroxide 50% | Hydrogen peroxide [USP] | Hydrogen peroxide solution |
| Hydrogen peroxide solution (DOT) | Hydrogen peroxide solution, 3%, for microbiology | Hydrogen peroxide solution, 30 % (w/w) in H2O, contains stabilizer |
| Hydrogen peroxide solution, 50 wt. % in H2O, stabilized | Hydrogen peroxide solution, >=30%, for trace analysis | Hydrogen peroxide solution, AR, contains sodium pyrophosphate as stabilizer, >=30 % (w/v) |
| Hydrogen peroxide solution, JIS special grade, 30.0-35.5% | Hydrogen peroxide solution, LR, contains sodium pyrophosphate as stabilizer, >=30 % (w/v) | Hydrogen peroxide solution, LR, contains sodium pyrophosphate as stabilizer, >=50 % (w/v) |
| Hydrogen peroxide solution, SAJ first grade, >=30.0% | Hydrogen peroxide solution, contains inhibitor, 30 wt. % in H2O, ACS reagent | Hydrogen peroxide solution, contains inhibitor, 30 wt. % in H2O, meets USP testing specifications |
| Hydrogen peroxide solution, contains inhibitor, 35 wt. % in H2O | Hydrogen peroxide solution, contains potassium stannate as inhibitor, 30-32 wt. % in water, semiconductor grade, 99.999% trace metals basis | Hydrogen peroxide solution, contains ~200 ppm acetanilide as stabilizer, 3 wt. % in H2O |
| Hydrogen peroxide solution, extra pure, 30.0-32.0% | Hydrogen peroxide solution, for ultratrace analysis | Hydrogen peroxide solution, meets analytical specification of Ph. Nord., 34.5-36.5% |
| Hydrogen peroxide solution, p.a., ACS reagent, reag. ISO, 30.0% | Hydrogen peroxide solution, puriss. p.a., ACS reagent, not stabilized, >=30% (RT) | Hydrogen peroxide solution, purum p.a., >=30% (RT) |
| Hydrogen peroxide solution, purum p.a., >=35% (RT) | Hydrogen peroxide solution, semiconductor grade MOS PURANAL(TM) (Honeywell 17937), >=30% | Hydrogen peroxide solution, semiconductor grade PURANAL(TM) (Honeywell 17948), >=30% |
| Hydrogen peroxide solution, semiconductor grade ULSI PURANAL(TM) (Honeywell 17024), >=30% | Hydrogen peroxide solution, semiconductor grade VLSI PURANAL(TM) (Honeywell 17606), >=30% | Hydrogen peroxide solution, tested according to Ph.Eur. |
| Hydrogen peroxide solutions | Hydrogen peroxide solutions (over 60% but not over 70%) | Hydrogen peroxide solutions (over 8% but not over 60%) |
| Hydrogen peroxide, 20% to 60% | Hydrogen peroxide, 3 wt.% solution in water, stabilized | Hydrogen peroxide, 3% |
| Hydrogen peroxide, 30% | Hydrogen peroxide, 6% in water | Hydrogen peroxide, 8% to 20% |
| Hydrogen peroxide, 90% | Hydrogen peroxide, ACS reagent, 30 wt% solution in water, nonstabilized | Hydrogen peroxide, aqueous solutions with >40% but not >60% hydrogen peroxide (stabilized as necessary) |
| Hydrogen peroxide, aqueous solutions with >40% but not >60% hydrogen peroxide (stabilized as necessary) [UN2014] [Oxidizer] | Hydrogen peroxide, aqueous solutions with >40% but not >60% hydrogen peroxide (stabilized as necessary) [UN2014] [Oxidizer] | Hydrogen peroxide, aqueous solutions with not <20% but not >40% hydrogen peroxide (stabilized as necessary) |
| Hydrogen peroxide, aqueous solutions with not <20% but not >40% hydrogen peroxide (stabilized as necessary) [UN2014] [Oxidizer] | Hydrogen peroxide, aqueous solutions with not <20% but not >40% hydrogen peroxide (stabilized as necessary) [UN2014] [Oxidizer] | Hydrogen peroxide, aqueous solutions with not <8% but <20% hydrogen peroxide (stabilized as necessary) |
| Hydrogen peroxide, aqueous solutions with not <8% but <20% hydrogen peroxide (stabilized as necessary) [UN2984] [Oxidizer] | Hydrogen peroxide, aqueous solutions with not <8% but <20% hydrogen peroxide (stabilized as necessary) [UN2984] [Oxidizer] | Hydrogen peroxide, pure, 50 wt% solution in water, stabilized |
| Hydrogen peroxide, solution | Hydrogen peroxide, solution, 3% | Hydrogen peroxide, solution, 30% |
| Hydrogen peroxide, solution, 35% | Hydrogen peroxide, stabilized or hydrogen peroxide aqueous solutions, stabilized with >60% hydrogen peroxide | Hydrogen peroxide, stabilized or hydrogen peroxide aqueous solutions, stabilized with >60% hydrogen peroxide [UN2015] [Oxidizer] |
| Hydrogen peroxide, stabilized or hydrogen peroxide aqueous solutions, stabilized with >60% hydrogen peroxide [UN2015] [Oxidizer] | Hydrogen peroxide, technical, 35 wt% solution in water, stabilized | Inhibine |
| Interox | Kastone | LS-2428 |
| Lase Peroxide | Lensan A | Lensept |
| MFCD00011333 | MHAJPDPJQMAIIY-UHFFFAOYSA-N | Magic Bleaching |
| Metrokur | Mirasept | MolMap_000025 |
| NSC 19892 | NSC-19892 | NSC19892 |
| Nite White Excel 2 | Odosat D | Opalescence Xtra |
| Oxigenal | Oxydol (JP17) | Oxyfull |
| Oxyfull (TN) | Oxysept | Oxysept I |
| PEO | Pegasyl | Perone |
| Perone 30 | Perone 35 | Perone 50 |
| Perossido di idrogeno | Perossido di idrogeno [Italian] | Peroxaan |
| Peroxan | Peroxclean | Peroxide |
| Peroxyde d'hydrogene | Peroxyde d'hydrogene [French] | Pre milk HP 0.5 |
| Pre milk HP 0.5 10 | Pre milk HP 1.0 | Puresept |
| Q1088474 | Q171877 | QTL1_000041 |
| Quasar Brite | Select Bleach | Superoxol |
| T-Stuff | TR-037767 | Teat dip HP 5 |
| UN 2014 (20%-52%) | UN 2015 (>52%) | UN 2984 (8%-20%) |
| UN2014 | UN2015 | UN2984 |
| UNII-BBX060AN9V | WLN: H2 O2 90% | Wasserstoffperoxid |
| Wasserstoffperoxid [German] | Waterstofperoxyde | Waterstofperoxyde [Dutch] |
| Whiteness HP | Whitespeed | Xtra White |
| [OH(OH)] | bis(hydridooxygen)(O--O) | dihydrogen peroxide |
| dihydrogen(peroxide) | dioxidane | hydrogen hydroperoxide |
| hydrogen per oxide | hydrogen peroxide | hydrogenperoxide |
| hydroperoxide | oxydol | perhydrol |
| DrugBank Name | Hydrogen peroxide |
| DrugBank | DB11091 |
| CAS Number | 7722-84-1, 8007-30-5 |
| PubChem Compound | 784 |
| KEGG Compound ID | C00027 |
| KEGG Drug | D00008 |
| PubChem.Substance | 347827892 |
| ChEBI | 16240 |
| PharmGKB | PA449917 |
| ChemSpider | 763 |
| Wikipedia | Hydrogen peroxide |
| HET | PEO |