Drug
D0256 | Carboxin
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| ELECTRON TRANSPORT CHAIN | affect | 71 | ||||||
| ELECTRON TRANSPORT CHAIN | bovine | heart mitochondria | affect | 192 | ||||
| GLUCOSE GALACTOSE IC50 RATIO | 3.1 | LUHMES (Lund human mesencephalic) cells | Glc–Gal–NeuriTox assay | EC25(NA) [Glc/Gal] | 326 | |||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Succinate dehydrogenase | 3.1 | LUHMES (Lund human mesencephalic) cells | Glc–Gal–NeuriTox assay | EC25(NA) [Glc/Gal] | 326 | |||
| Quinone pocket | inhibitor | 71 | ||||||
| Quinone pocket | bovine | heart mitochondria | inhibitor | 192 | ||||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 214 companies from 6 notifications to the ECHA C&L Inventory. Reported as not meeting GHS hazard criteria by 1 of 214 companies. For more detailed information, please visit ECHA C&L website Of the 5 notification(s) provided by 213 of 214 companies with hazard statement code(s): H302 (92.02%): Harmful if swallowed [Warning Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - wild | LD50 | oral | 42200ug/kg (42.2mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
| rat | LD50 | oral | 430mg/kg (430mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(2), Pg. 55, 1979. | |
| chicken | LD50 | oral | 24gm/kg (24000mg/kg) | Veterinariya. Veterinary Science. Vol. 54(6), Pg. 85, 1978. | |
| mammal (species unspecified) | LD50 | unreported | 3200mg/kg (3200mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 423, 1971. | |
| rat | LD50 | skin | 1050mg/kg (1050mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(2), Pg. 55, 1979. | |
| mouse | LD50 | oral | 3200mg/kg (3200mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(2), Pg. 55, 1979. | |
| rat | LC50 | inhalation | > 20gm/m3/1H (20000mg/m3) | Pesticide Manual. Vol. 9, Pg. 130, 1991. | |
| rabbit | LD50 | skin | 8gm/kg (8000mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1104, 1986. | |
| (6-methyl(2,3-dihydro-1,4-oxathiin-5-yl))-N-benzamide | 1, 2,3-dihydro-5-carboxanilido-6-methyl- | 1, 5,6-dihydro-2-methyl- |
| 1, 5,6-dihydro-2-methyl-N-phenyl- | 1,4-Oxathiin, 2,3-dihydro-5-carboxanilido-6-methyl- | 1,4-Oxathiin-3-carboxamide, 5,6-dihydro-2-methyl-N-phenyl- |
| 1,4-Oxathiin-3-carboxanilide, 5,6-dihydro-2-methyl- | 1,4-Oxathiin-3-carboxanilide, 5,6-dihydro-2-methyl- (8CI) | 2,3-Dihydro-5-carboxanilido-6-methyl-1,4-oxathiin |
| 2,3-Dihydro-6-methyl-1,4-oxathiin-5-carboxanilide | 2,3-Dihydro-6-methyl-5-phenylcarbamoyl-1,4-oxathiin | 2,4-oxathiin |
| 2,4-oxathiin-5-carboxanilide | 2-Methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide | 2-Methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide # |
| 234C684 | 5,4-oxathiin-3-carboxanilide | 5,6-DIHYDRO-2-METHYL-1,4-OXATHIIN-3-CARBOXANILID |
| 5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilide | 5,6-Dihydro-2-methyl-3-carboxanilido-1,4-oxathiin | 5,6-Dihydro-2-methyl-3-carboxanilido-1,4-oxathiin [German] |
| 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide | 5-19-07-00251 (Beilstein Handbook Reference) | 5-Carboxanilido-2,3-dihydro-6-methyl-1,4-oxathiin |
| 5-Carboxanilido-2,4-oxathiin | 5234-68-4 | 5A8K850HDE |
| 6-methyl-N-phenyl-2,3-dihydro-1,4-oxathiin-5-carboxamide | 6-methyl-N-phenyl-2,3-dihydro-1,4-oxathiine-5-carboxamide | A829041 |
| AB00083271-01 | AB00083271-08 | AB0016465 |
| AC-12556 | AK-32289 | AKOS000545990 |
| AM20060655 | BR-32289 | BRD-K17610834-001-01-2 |
| BRN 0983249 | C11255 | CARBOXIN |
| CARBOXIN | CAS-5234-68-4 | CBX |
| CCG-236658 | CCRIS 5217 | CHEBI:3405 |
| CHEMBL1231667 | CS-W019702 | Cambridge id 5373048 |
| Carbathiin | Carboxin 10 microg/mL in Cyclohexane | Carboxin [ANSI:BSI:ISO] |
| Carboxine | Carboxine Form II | Carboxine [ISO-French] |
| Carboxine, PESTANAL(R), analytical standard | Caswell No. 165A | Cerevax |
| Cerevax Extra | D 735 | D-735 |
| D735 | DB-052115 | DB04657 |
| DCMO | DMOC | DMOC (VAN) |
| DNDI1724944 | DSSTox_CID_3951 | DSSTox_GSID_23951 |
| DSSTox_RID_77240 | DTXSID0023951 | Dual Murganic RPB |
| EINECS 226-031-1 | EPA Pesticide Chemical Code 090201 | Enhance |
| Enhance Plus | F 735 | FS-3015 |
| FT-0602928 | Fenoxan | Flo pro v seed protectant |
| GYSSRZJIHXQEHQ-UHFFFAOYSA-N | Germate Plus | HMS1538M06 |
| HMS2231N20 | HMS3370C04 | HMS3604G19 |
| HSDB 1532 | HY-B2064 | KS-00000JG9 |
| Karboxyn | Kemikar | Kisvax |
| LS-99691 | MCULE-1167484479 | MLS000059188 |
| Mist-O-Matic Murganic | Murganic | N-Phenyl-2-methyl-5,6-dihydrooxathiin-3-carboxamide |
| NCGC00053919-02 | NCGC00053919-03 | NCGC00053919-04 |
| NCGC00053919-05 | NCGC00053919-06 | NCGC00254614-01 |
| NCGC00259537-01 | NSC 263492 | NSC-263492 |
| NSC263492 | O451 | Oxatin |
| Pesticide5_Carboxin_C12H13NO2S_Vitavax | Pro-Gro | Q2937968 |
| RTV Vitavax | S-2030 | SBB056737 |
| SCHEMBL18392 | SDCCGMLS-0037038.P002 | SMR000069560 |
| SR-01000388704 | SR-01000388704-1 | ST020597 |
| ST2412721 | STK838152 | TimTec1_001678 |
| Tox21_201988 | Tox21_300706 | UNII-5A8K850HDE |
| V 4X | Vitaflo 250 | Vitaflow |
| Vitavax | Vitavax 100 | Vitavax 30-C |
| Vitavax 34 | Vitavax 735D | Vitavax 75W |
| Vitavax EC 200 | Vitavax-200 | Vitavax-300 |
| Vitavax-Thiram-Lindane | W-105831 | WLN: T6O DS BUTJ B1 CVMR |
| ZINC43478 |