Drug
D0479 | ethynodiol diacetate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 15.40±0.84 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 21.82 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| ELECTRON TRANSPORT CHAIN | rat | isolated liver mitochondria | measurements of mitochondrial respiration; RST inhibition assay, RST uncoupling assay; IC 50ratio of glucose/galactose assay | decrease | 53 | |||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Danger |
Aggregated GHS information provided by 57 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (96.49%): Harmful if swallowed [Warning Acute toxicity, oral] H312 (96.49%): Harmful in contact with skin [Warning Acute toxicity, dermal] H332 (96.49%): Harmful if inhaled [Warning Acute toxicity, inhalation] H351 (100%): Suspected of causing cancer [Warning Carcinogenicity] H360 (29.82%): May damage fertility or the unborn child [Danger Reproductive toxicity] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P330, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate | (3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol diacetate | (3S,8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate |
| (3beta,17alpha)-19-Norpregn-4-en-20-yne-3,17-diyl diacetate | (3beta,17beta)-17-ethynylestr-4-ene-3,17-diyl diacetate | 17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol diacetate |
| 17-alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate | 17-alpha-Ethynyl-4-estrene-3-beta,17-beta-diol diacetate | 17-alpha-Ethynylestr-4-ene-3-beta,17-beta-diol acetate |
| 17a-Ethynyl-4-estren-3b,17-diol diacetate | 17alpha-Ethynyl-19-norandrost-4-ene-3beta,17-beta-diol diacetate | 17alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate |
| 17alpha-Ethynyl-4-estrene-3beta,17beta-diol diacetate | 17alpha-Ethynylestr-4-ene-3beta,17beta-diol acetate | 17alpha-ethynylestr-4-ene-3beta,17beta-diyl diacetate |
| 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol diacetate | 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol, diacetate | 19-Nor-17alpha-pregn-4-en-20-yne-3beta,17-diol diacetate |
| 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3b,17a)- | 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3beta,17alpha)- | 19-norpregn-4-en-20-yn-3beta,17alpha-diol, diacetate |
| 297-76-7 | 297E767 | 3-beta, 17-beta-Diacetoxy-17-alpha-ethynyl-4-oestrene |
| 3-beta,17-beta-Diacetoxy-19-nor-17-alpha-pregn-4-en-20-yne | 3beta, 17beta-Diacetoxy-17alpha-ethynyl-4-oestrene | 3beta,17beta-Diacetoxy-19-nor-17alpha-pregn-4-en-20-yne |
| 62H10A1236 | 8080 C. B | 8080 C. B. |
| 8080 CB | A820050 | AB00513958 |
| AB00513958_02 | AK129080 | AKOS015895252 |
| AS-13382 | B1508 | BCP10923 |
| BDBM50237627 | BPBio1_000832 | BSPBio_000756 |
| C-21409 | C12724 | CAS-297-76-7 |
| CC-28314 | CCG-220908 | CCRIS 305 |
| CHEBI:31580 | CHEMBL1200624 | CS-4640 |
| Cervicundin | Continuin | D01294 |
| DB00823 | DSSTox_CID_614 | DSSTox_GSID_20614 |
| DSSTox_RID_75690 | DTXSID4020614 | EBD2209572 |
| EINECS 206-044-9 | ETHYNODIOL DIACETATE | Ethinodiol diacetate |
| Ethynodiol (diacetate) | Ethynodiol acetate | Ethynodiol diacetate (JAN/USP) |
| Ethynodiol diacetate [Progestins] | Ethynodiol diacetate [USAN:USP] | Ethynodiol diacetate [USAN] |
| Ethynodiol diacetate, United States Pharmacopeia (USP) Reference Standard | Etynodiol Acetate | Etynodiol di(acetate) |
| Etynodiol diacetate | Femulen | GTPL7072 |
| HMS1570F18 | HMS2097F18 | HMS3714F18 |
| HY-B1089 | I036 | J-017631 |
| LMST02030124 | LS-7392 | Luto-metrodiol |
| MLS000028661 | Metrodiol | Metrodiol diacetate |
| NCGC00166138-01 | NCGC00166138-02 | NCGC00166138-04 |
| NCGC00166138-05 | NCGC00186466-01 | ONKUMRGIYFNPJW-KIEAKMPYSA-N |
| Ovulen 50 | Prestwick0_000908 | Prestwick1_000908 |
| Prestwick2_000908 | Prestwick3_000908 | Q5405160 |
| SC 11800 | SC-11800 | SCHEMBL40888 |
| SMR000058858 | SPBio_002955 | SR-01000872687 |
| SR-01000872687-1 | Tox21_112333 | Tox21_112333_1 |
| Tox21_112924 | UNII-62H10A1236 | ZINC3876023 |
| [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate | [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ethanoate | acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester; |
| ethynodiol-diacetate | s3160 |