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Drug

D0530 | HQNO

Molecular Formula C16H21NO2
Molecular Weight 259.34
Structure
Trade names 2-heptyl-4-hydroxyquinoline n-oxide
Description complex II inhibitor

Toxicity Dose Time Species Model Method Action Positive criterion Reference
ELECTRON TRANSPORT CHAIN affect 74
ELECTRON TRANSPORT CHAIN bovine heart mitochondria affect 192

Target Dose Time Species Model Method Action Positive criterion Reference
Quinone pocket inhibitor 74
Quinone pocket bovine heart mitochondria inhibitor 192

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intraperitoneal 40mg/kg (40mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 5, Pg. 169, 1981.


  • 1-Hydroxy-2-heptylquinoline-4(1H)-one 1-hydroxy-2-heptyl-4-quinolone 1FU5S5CG6A
    2-(n-Heptyl)-4-hydroxyquinoline N-oxide 2-HEPTYL-1-OXY-QUINOLIN-4-OL 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE
    2-HEPTYL-4-HYDROXYQUINOLINE-1-OXIDE 2-Heptyl-1-hydroxyquinolin-4(1H)-one 2-Heptyl-4-hydroxyquinoline oxide
    2-Heptyl-4-hydroxyquinoline-N-oxide 2-Heptyl-4-quinolinol 1-oxide 2-heptyl-4-hydroxyquinoline 1-oxide
    2-heptyl-4-hydroxyquinoline n-oxide 2-heptylquinolin-4-ol 1-oxide 2-n-heptyl-4-hydroxyquinoline-N-oxide
    341-88-8 4-Quinolinol, 2-heptyl-, 1-oxide 4-Quinolinol,2-heptyl-, 1-oxide
    BRN 1466419 C04284 CHEBI:28362
    CHEMBL1233401 CTK4H1880 DB07918
    DTXSID20955644 HOQNO J-019483
    KF 8940 LS-142541 Pyo II
    Q27097153; SCHEMBL21065453 SCHEMBL429766
    UNII-1FU5S5CG6A VQ10117 ZINC000001529909
    ZINC1529909 ZINC28541300 hqno

    CAS Number 341-88-8, 642-15-9
    PubChem Compound 1561
    KEGG Compound ID C04284
    ChEBI 28362