Compound
D0543 | strobilurin a
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| ELECTRON TRANSPORT CHAIN | affect | 84 | ||||||
| ELECTRON TRANSPORT CHAIN | >100 nmol/mg | bovine | mitochondria | NADH–Q | decrease | IC50 | 99 | |
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| NADH:ubiquinone reductase | >100 nmol/mg | bovine | mitochondria | NADH–Q | inhibitor | IC50 | 99 | |
| Qo site (Qp site or ubiquinol oxidation site) | mobile conformation | 84 | ||||||
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 500mg/kg (500mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 6, Pg. 267, 1981. | |
| mouse | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 6, Pg. 267, 1981. | |
| 15143I0275 | 3,5-Hexadienoic acid, 2-(methoxymethylene)-3-methyl-6-phenyl-, methyl ester, (2E,3Z,5E)- | 3,5-Hexadienoic acid, 2-(methoxymethylene)-3-methyl-6-phenyl-, methyl ester, (E,E,E)- |
| 52110-55-1 | CHEBI:78156 | LS-93712 |
| Mucidermin | Mucidin | OM-1 |
| Q27147658 | SCHEMBL1313193 | STROBILURIN A |
| UNII-15143I0275 | UNII-44HO7DSH8E component JSCQSBGXKRTPHZ-SYKZHUKTSA-N | methyl (2E,3Z,5E)-2-(methoxymethylene)-3-methyl-6-phenylhexa-3,5-dienoate; |
| CAS Number | 52110-55-1 |
| PubChem Compound | 6437379 |