Compound

D1073 | pyraclostrobin

Molecular Formula C19H18ClN3O4
Molecular Weight 387.8
Structure
Description carbamate ester; fungicide; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic; a methoxycarbanilate strobilurin antifungal agent and a carbanilate fungicide

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 6.35±1.92 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 1.26 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 9.04±1.89 rat hepatocytes MMP assay decrease IC50 163
GLUCOSE GALACTOSE IC50 RATIO 50µM permeabilized LUHMES cells Assessment of the function of individual mitochondrial complexes using Agilent Seahorse XFe24 326

Target Dose Time Species Model Method Action Positive criterion Reference
Quinol--cytochrome-c reductase 50µM permeabilized LUHMES cells Assessment of the function of individual mitochondrial complexes using Agilent Seahorse XFe24 inhibit 326

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 338 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H315 (99.11%): Causes skin irritation [Warning Skin corrosion/irritation]


H331 (99.11%): Toxic if inhaled [Danger Acute toxicity, inhalation]


H335 (24.85%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


H400 (83.73%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P271, P273, P280, P302+P352, P304+P340, P311, P312, P321, P332+P313, P362, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H316: Causes mild skin irritation [Warning Skin corrosion/irritation]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P260, P261, P264, P270, P271, P304+P340, P307+P311, P311, P314, P321, P332+P313, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 013P180 175013-18-0 4CH-024111
    9060AA AC-27490 ACM175013180
    AKOS015895785 ANW-66330 AX8149586
    C18561 CAS-175013-18-0 CHEBI:78780
    CHEMBL519873 CTK8C1356 Cabrio
    Carbamic acid, (2-(((1-(4-chlorophenyl)-1H-pyrazol-3-yl)oxy)methyl)phenyl)methoxy-, methyl ester Carbamic acid, N-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]-N-methoxy-, methyl ester; DJW8M9OX1H
    DNDI1724943 DSSTox_CID_12638 DSSTox_GSID_32638
    DSSTox_RID_79017 DTXSID7032638 FT-0654374
    HSDB 7497 HZRSNVGNWUDEFX-UHFFFAOYSA-N Headline
    J-011054 KS-0000016W LS-49173
    Methyl (2-(((1-(4-chlorophenyl)-1H-pyrazol-3-yl)oxy)methyl)phenyl)(methoxy)carbamate Methyl N-(2-(1-(4-chlorophenyl)-1H-pyrazol-3-yloxymethyl)phenyl)-(N-methoxy)carbamate NCGC00163895-01
    NCGC00163895-02 NCGC00163895-03 NCGC00163895-04
    NCGC00255029-01 Pyrachlostrobin Pyraclostrobin
    Pyraclostrobin 10 microg/mL in Acetonitrile Pyraclostrobin [ISO:BSI] Pyraclostrobin, PESTANAL(R), analytical standard
    Pyraclostrobine Q1961265 RT-015160
    SCHEMBL18441 Tox21_301130 UNII-DJW8M9OX1H
    ZINC2511853 methyl N-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-N-methoxy-carbamate methyl N-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-N-methoxycarbamate
    methyl [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamate

    CAS Number 175013-18-0
    PubChem Compound 6422843
    KEGG Compound ID C18561
    ChEBI 78780