F0109 | Redox cycling
Transmembrane potential >> redox cycling
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Hydroxynaphthoquinones | Positive | 204 | |||||||
| Naphthoquinone | Positive | 204 | |||||||
| Anthracene‐9,10‐diones | Positive | 223 | |||||||
| Quinones | Positive | 224 | |||||||
| Doxorubicin | Positive | 278 | |||||||
| Isoniazid | Positive | 278 | |||||||
| Gentamicin | Positive | 278 | |||||||
| Menadione | Positive | 278 | |||||||
| Hydronaphthoquinone | rat | liver mitochondria | RST assay( Respiratory Screening Technology)-measurement of oxygen consumption in isolated mitochondria using a phosphorescent oxygen-sensitive probe A65N-1 | affect | Positive | 204 | |||
| Naphthoquinone | rat | liver mitochondria | RST assay( Respiratory Screening Technology)-measurement of oxygen consumption in isolated mitochondria using a phosphorescent oxygen-sensitive probe A65N-1 | affect | Positive | 204 | |||