F020105 | DNP-uncoupled respiration
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Nitrofurantoin | 0.005mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| Nitrofurantoin | 1 mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| Nitrofurantoin | 0.05mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| Nitrofurantoin | 1 mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| Nitrofurantoin | 0.05mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| nitrofurazone | 1mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| nitrofurazone | 1mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |
| Nitrofurantoin | 1 mM | mouse; C57B/6J | liver mitochondria | Measurement of oxygen uptake | decrease | Positive | p < 0.05 | 13 | |