GO:0006127
Function of mitochondria >> Transport >> Metabolite transport >> s,n-glycerophosphate shuttle

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
lovastatin				C2C12 myoblasts		affect	Positive		180
Simvastatin				C2C12 myoblasts		affect	Positive		180
1h-benzimidazol-5-amine-2-4-aminophenyl	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-(Dimethylamino)-1,3-benzothiazol-6-ol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]phenol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
7,8-Dihydroxy-4-methylcoumarin	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Amino-2-(5-ethyl-benzooxazol-2-yl)-phenol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(4-Methoxyphenyl)-[2-(p-anisidino)ethyl]amine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
3,3'-Diamino-4,4'-dihydroxydiphenyl Sulfone	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-(4-Hydroxy-1H-indol-3-yl)acetamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2,5-Bis(2-phenylacetamido)terephthalic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2,6-Dimethyl-5,12-dihydroindolo[3,2-d][1,3]benzodiazepine;hydrochloride	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-2,4-dimethoxybenzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N'-(4-Methoxybenzyl)-N,N-dimethylbenzene-1,3-diamine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-(1,2,3,4-Tetrahydro-benzo[a]phenanthridin-5-yl)-benzene-1,2-diol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-Benzyl-4-methoxyaniline	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Methyl 2-amino-4-ethyl-5-methylthiophene-3-carboxylate	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Chloro-N-(2-hydroxyphenyl)benzenesulfonamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(4-Hydroxyphenyl)furan-2-carboxamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(Z)-2-Cyano-3-(3-ethoxy-4-hydroxyphenyl)prop-2-enamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(3-Bromo-4-hydroxyphenyl)[(4-chlorophenyl)sulfonyl]amine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Chloro-6-methylindolo[1,2-c]quinazolin-12-amine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-(2,3-Dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)benzene-1,2-diol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(5E)-5-(4-Hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
8-Chloro-2,2-dimethyl-2,3-dihydro-1H-phenothiazin-4(10H)-one	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[(3,4-Dimethylphenyl)sulfonyl]benzene-1,4-diol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-([4-(1H-Benzimidazol-2-yl)phenyl]amino)-4-oxobutanoic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Ethyl 2-ethoxy-5-hydroxy-1H-indole-3-carboxylate	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-(1,2,3,4-Tetrahydrobenzo[a]phenanthridin-5-yl)benzene-1,3-diol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(Cyclohexylmethyl)-4-methoxyaniline	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(Furan-2-ylmethyl)-1,3-benzodioxol-5-amine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
5-Nitro-2-phenyl-1H-indole	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
8-Chloro-2,3-dihydro-1H-phenothiazin-4(10H)-one	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(4-Bromophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[2-(2-Aminophenyl)vinyl]-5,7-dimethylquinolin-8-ol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4,6-Dimethyl-2-phenyl-2H-pyrazolo[3,4-b]pyridin-3-ol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Methoxy-2-[(4-piperidylpiperidyl)methyl]phenol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-3-nitrobenzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Amino-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(NE)-N-[[3-[[3-[(E)-hydroxyiminomethyl]-2,4,6-trimethylphenyl]methyl]-2,4,6-trimethylphenyl]methylidene]hydroxylamine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(3-Fluorophenyl)-2,4,6-tri(propan-2-yl)benzenesulfonamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-(4-Hydroxy-3-methoxybenzylidene)-1H-indene-1,3(2H)-dione	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-1H-isoindole-1,3(2H)-dione	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Furancarboxamide, N-[[(4-methoxyphenyl)amino]thioxomethyl]-	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Amino-N-quinolin-8-yl-benzenesulfonamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(5Z)-5-[(4-Fluorophenyl)methylidene]-1-methyl-3-phenyl-1,3-diazinane-2,4,6-trione	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[4-(1-Adamantyl)phenoxy]-N,N-diethylethanamine;hydrochloride	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(2Z)-2-(Acetylamino)-N-(4-hydroxyphenyl)-3-phenylprop-2-enamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(5E)-5-[(3-Bromo-4-methoxyphenyl)methylidene]-1-phenyl-2-sulfanylidene-1,3-diazinane-4,6-dione	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
[(3-{[(4-Bromophenyl)amino]carbonyl}phenyl)thio]acetic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[(4-Chlorobenzyl)thio]-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
1-(5-Hydroxy-2-methyl-1-phenyl-1H-indol-3-yl)ethanone	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[(4-Ethylpiperazin-1-yl)methyl]-4-methoxyphenol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-(4-Fluorophenyl)-1,3,5-trimethyl-2,6-diphenylpiperidin-4-ol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-[(E)-1-[5-(4-Bromophenyl)furan-2-yl]-3-[3-(dimethylamino)propylamino]-3-oxoprop-1-en-2-yl]-4-methylbenzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
(2Z)-3-{N-[4-(4-Chlorophenyl)phenyl]carbamoyl}prop-2-enoic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-[(E)-3-(4-Ethylpiperazin-1-yl)prop-1-enyl]-N,N-dimethylaniline	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
1,5-Dihydro-4,5-diphenyl-2H-imidazol-2-one	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-[(E)-2-(4-Chlorophenyl)ethenyl]-1-methyl-1H-benzimidazole	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-[1-Azabicyclo[2.2.2]octan-3-ylidene-[4-(dimethylamino)phenyl]methyl]-N,N-dimethylaniline;hydrochloride	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Oxo-4-((4-(styryl)phenyl)amino)but-2-enoic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2,5-Dianilinoterephthalic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Methoxy-N-[4-(thiazol-2-ylsulfinamoyl)-phenyl]-benzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
3-[(3,4-Dimethylphenyl)sulfonyl]propanenitrile	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-[4-(1,3-Benzoxazol-2-yl)anilino]-4-oxobutanoic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
1-(3-Chlorophenyl)-2,3,4,5,6,7,8,8a-octahydro-1H-isoquinolin-4a-ol;hydrochloride	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
6-Methyl-2-(1,2,2,2-tetrafluoroethyl)-1H-benzimidazole	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Ethyl 6-amino-5-cyano-2-methyl-4-(2-nitrophenyl)-4H-pyran-3-carboxylate	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(2,1,3-Benzoxadiazol-4-yl)-2,2,2-trifluoroacetamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-Tert-butyl-N-(4-methylphenyl)benzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Methoxy-4-(morpholin-4-ylmethyl)phenol	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Bis((1E)-2-phenylvinyl)phosphinic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
1-[2-(Allyloxy)benzyl]-4-benzylpiperidine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2,5-Diaminoterephthalic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-(1-Adamantylcarbonyl)-N'-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)thiourea	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-(Isobutylthio)succinic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-{4-[Acetyl(methyl)amino]phenyl}-4-biphenylcarboxamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
4-[(E)-3-(2-Ethylpiperidin-1-yl)prop-1-enyl]-N,N-dimethylaniline	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
3-(2-Chloro-phenyl)-2-(4-(2-oxo-2H-chromen-3-YL)-thiazol-2-YL)-acrylonitrile	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Ethyl (7Z)-2-amino-7-(hydroxyimino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Amino-4-(3,4-dichlorophenyl)thiazole	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
5-(2-Nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
3-(4-Bromo-2-thienyl)-2-cyano-2-propenethioamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
Benzyl [(6-amino-3,5-dicyano-4-ethylpyridin-2-yl)sulfanyl]acetate	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
N-{2-[(1,3-Diphenyl-1H-pyrazol-5-yl)amino]phenyl}benzamide	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Butyl-5-methylisophthalic acid	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Butylsulfanyl-6-methyl-9H-1,3,4,9-tetraaza-fluorene	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162
2-Phenyldipyrrolo[1,2-a:2',1'-c]pyrazine	∼2.5 µM		rat	skeletal muscle mitochondria	measurement of superoxide/H2O2 production	affect	Positive		162

Associated Targets

T181. Glycerol-3-phosphate dehydrogenase, mitochondrial