F021216 | ATP/ADP ratio

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Berberine 10 μM 24 hr K1735-M2 mouse melanoma cells An acid extraction procedure was used to evaluate the intracellular concentration of adenine nucleotides. Adenine nucleotides were separated by reverse-phase high-performance liquid chromatography. Quantification was achieved by employing ATP, ADP, and AMP standard curves. decrease Positive p< 0.05 vs. control for each time of incubation 327