Oxidative stress >> Liver-specific oxidative stress

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
Acetaminophen	300 mg/kg	3 hours	mice; C57Bl/6	in vivo	ALT activity measurement	increase	Positive	p < 0.05	1
Acetaminophen	300 mg/kg	6 hours	mice; C57Bl/6	in vivo	ALT activity measurement	increase	Positive	p < 0.05	1
Acetaminophen	300 mg/kg	24 hours	mice; C57Bl/6	in vivo	ALT activity measurement	increase	Positive	p < 0.05	1
Acetaminophen	1.5 g/kg	24 hours	rat; Fischer (F344)	in vivo	ALT activity measurement	increase	Positive	p < 0.05	1