F060102 | Mitochondrial DNA metabolic process

GO:0006264
Mitochondrial DNA >> Mitochondrial DNA maintainance >> mitochondrial DNA metabolic process

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Emtricitabine Positive 194
Ciprofloxacin decrease Positive 307
Menadione 6.0 μM 1 hours human pFastBac Meassurement of DNA polymerase gamma activity affect Positive IC50 9
Abacavir Positive 185
Zalcitabine Positive 194
Didanosine Positive 194
Stavudine Positive 194
Lamivudine Positive 194
Tenofovir Positive 194
Zidovudine Positive 194
Carbovir Positive 194
Abacavir Positive 194
Fialuridine Positive 194