Cell death >> Apoptosis >> late apoptosis

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
Amiodarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.01	4
benzarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.01	4
benzbromarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.01	4
Amiodarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.05	4
benzarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.05	4
benzbromarone	100 μmol/L	8 hours	rat; Sprague–Dawley	hepatocytes	Apoptosis measurement	increase	Positive	p < 0.01	4
Clotrimazole	30 μmol/L	24 hours	human	CAL27	Apoptosis measurement	increase	Positive	p < 0.05	5
Clotrimazole	30 μmol/L	24 hours	human	SCC25	Apoptosis measurement	increase	Positive	p < 0.05	5
Clotrimazole	30 μmol/L	24 hours	human	UM1	Apoptosis measurement	increase	Positive	p < 0.05	5
Clotrimazole	40 μmol/L	24 hours	human	CAL27	Apoptosis measurement	increase	Positive	p < 0.01	5
Clotrimazole	40 μmol/L	24 hours	human	SCC25	Apoptosis measurement	increase	Positive	p < 0.01	5
Clotrimazole	40 μmol/L	24 hours	human	UM1	Apoptosis measurement	increase	Positive	p < 0.01	5