301. |
A High-Throughput Screening Identifies MICU1 Targeting Compounds. |
Di Marco, Giulia; Vallese, Francesca; Jourde, Benjamin; Bergsdorf, Christian; Sturlese, Mattia; De Mario, Agnese; Techer-Etienne, Valerie; Haasen, Dorothea; Oberhauser, Berndt; Schleeger, Simone; Minetti, Giulia; Moro, Stefano; Rizzuto, Rosario; De Stefani, Diego; Fornaro, Mara; Mammucari, Cristina |
Cell reports |
2020 |
10.1016/j.celrep.2020.01.081 |
302. |
DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter. |
Kon, Naohiro; Murakoshi, Michiko; Isobe, Aya; Kagechika, Katsuji; Miyoshi, Naoki; Nagayama, Takahiro |
Cell death discovery |
2017 |
10.1038/cddiscovery.2017.45 |
303. |
Inhibition of mitochondrial function in isolated rat liver mitochondria by azole antifungals |
Rodriguez, Rosita J.; Acosta, Daniel |
Journal of biochemical toxicology |
1905 |
10.1002/(SICI)1522-7146(1996)11:3<127::AID-JBT4>3.0.CO;2-M |
304. |
Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus. |
Shekhova, Elena; Kniemeyer, Olaf; Brakhage, Axel A |
Antimicrobial Agents and Chemotherapy |
2017 |
10.1128/AAC.00978-17 |
305. |
Toxicity and Loss of Mitochondrial Membrane Potential Induced by Alkyl Gallates in Trypanosoma cruzi. |
Andr?o, Rog?rio; Regasini, Lu?s Oct?vio; Petr?nio, Maicon Segalla; Chiari-Andr?o, Bruna Galdorfini; Tansini, Aline; Silva, Dulce Helena Siqueira; Cicarelli, Regina Maria Barretto |
International scholarly research notices |
2015 |
10.1155/2015/924670 |
306. |
High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins. |
Tolosa, Laia; Carmona, Antonio; Castell, Jos? V; G?mez-Lech?n, M Jos?; Donato, M Teresa |
Archives of Toxicology |
2015 |
10.1007/s00204-014-1334-3 |
307. |
Impact of pharmacological agents on mitochondrial function: a growing opportunity? |
Stoker, Megan L; Newport, Emma; Hulit, James C; West, A Phillip; Morten, Karl J |
Biochemical Society Transactions |
2019 |
10.1042/BST20190280 |
308. |
Mitochondrial dynamics: biogenesis, fission, fusion, and mitophagy in the regulation of stem cell behaviors. |
Fu, Wenyan; Liu, Yang; Yin, Hang |
Stem cells international |
2019 |
10.1155/2019/9757201 |
309. |
Bottom-line mechanism of organochlorine pesticides on mitochondria dysfunction linked with type 2 diabetes. |
Ko, Eun; Choi, Moonsung; Shin, Sooim |
Journal of hazardous materials |
2020 |
10.1016/j.jhazmat.2020.122400 |
310. |
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. |
Qi, Xin; Qvit, Nir; Su, Yu-Chin; Mochly-Rosen, Daria |
Journal of Cell Science |
2013 |
10.1242/jcs.114439 |
311. |
Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. |
Filichia, Emily; Hoffer, Barry; Qi, Xin; Luo, Yu |
Scientific Reports |
2016 |
10.1038/srep32656 |
312. |
Gentamicin rapidly inhibits mitochondrial metabolism in high-frequency cochlear outer hair cells. |
Jensen-Smith, Heather C; Hallworth, Richard; Nichols, Michael G |
Plos One |
2012 |
10.1371/journal.pone.0038471 |
313. |
A high-throughput real-time in vitro assay using mitochondrial targeted roGFP for screening of drugs targeting mitochondria. |
Chandrasekharan, Aneesh; Varadarajan, Shankara Narayanan; Lekshmi, Asha; Lupitha, Santhik Subhasingh; Darvin, Pramod; Chandrasekhar, Leena; Pillai, Prakash Rajappan; Santhoshkumar, T R; Pillai, M Radhakrishna |
Redox biology |
1905 |
10.1016/j.redox.2018.10.013 |
314. |
Small-molecule inhibitors of human mitochondrial DNA transcription. |
Bonekamp, Nina A; Peter, Bradley; Hillen, Hauke S; Felser, Andrea; Bergbrede, Tim; Choidas, Axel; Horn, Moritz; Unger, Anke; Di Lucrezia, Raffaella; Atanassov, Ilian; Li, Xinping; Koch, Uwe; Menninger, Sascha; Boros, Joanna; Habenberger, Peter; Giavalisco, Patrick; Cramer, Patrick; Denzel, Martin S; Nussbaumer, Peter; Klebl, Bert; Falkenberg, Maria; Gustafsson, Claes M; Larsson, Nils-G?ran |
Nature |
2020 |
10.1038/s41586-020-03048-z |
315. |
Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death. |
Esterberg, Robert; Linbo, Tor; Pickett, Sarah B; Wu, Patricia; Ou, Henry C; Rubel, Edwin W; Raible, David W |
The Journal of Clinical Investigation |
2016 |
10.1172/JCI84939 |
316. |
Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells. |
O'Reilly, Molly; Young, Luke; Kirkwood, Nerissa K; Richardson, Guy P; Kros, Corn? J; Moore, Anthony L |
Frontiers in Cellular Neuroscience |
2019 |
10.3389/fncel.2019.00416 |
317. |
In vitro toxicity of alternative oxidase inhibitors salicylhydroxamic acid and propyl gallate on Fusicladium effusum |
Seyran, Murat; Brenneman, Timothy B.; Stevenson, Katherine L. |
Journal of pest science |
2010 |
10.1007/s10340-010-0312-7 |
318. |
Control of the citric acid cycle by glyoxylate. Mechanism of the inhibition by oxalomalate and gamma-hydroxy-alpha-oxoglutarate. |
Ruffo, A; Testa, E; Adinolfi, A; Pelizza, G; Moratti, R |
The Biochemical Journal |
1967 |
10.1042/bj1030019 |
319. |
1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity. |
Arn?r, E S; Bj?rnstedt, M; Holmgren, A |
The Journal of Biological Chemistry |
1995 |
10.1074/jbc.270.8.3479 |
320. |
Selective disruption of mitochondrial thiol redox state in cells and in?vivo. |
Booty, Lee M; Gawel, Justyna M; Cvetko, Filip; Caldwell, Stuart T; Hall, Andrew R; Mulvey, John F; James, Andrew M; Hinchy, Elizabeth C; Prime, Tracy A; Arndt, Sabine; Beninca, Cristiane; Bright, Thomas P; Clatworthy, Menna R; Ferdinand, John R; Prag, Hiran A; Logan, Angela; Prudent, Julien; Krieg, Thomas; Hartley, Richard C; Murphy, Michael P |
Cell Chemical Biology |
2019 |
10.1016/j.chembiol.2018.12.002 |
321. |
Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation? |
L?storff, J; Schlimme, E |
Experientia |
1976 |
10.1007/BF01940801 |
322. |
Therapeutic potential of coenzyme Q10 in mitochondrial dysfunction during tacrolimus-induced beta cell injury. |
Luo, Kang; Yu, Ji Hyun; Quan, Yi; Shin, Yoo Jin; Lee, Kyung Eun; Kim, Hong Lim; Ko, Eun Jeong; Chung, Byung Ha; Lim, Sun Woo; Yang, Chul Woo |
Scientific Reports |
2019 |
10.1038/s41598-019-44475-x |
323. |
Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria. |
Simon, Nicolas; Morin, Christophe; Urien, Sa?k; Tillement, Jean-Paul; Bruguerolle, Bernard |
British Journal of Pharmacology |
2003 |
10.1038/sj.bjp.0705038 |
324. |
Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis. |
Warne, Justin; Pryce, Gareth; Hill, Julia M; Shi, Xiao; Lenner?s, Felicia; Puentes, Fabiola; Kip, Maarten; Hilditch, Laura; Walker, Paul; Simone, Michela I; Chan, A W Edith; Towers, Greg J; Coker, Alun R; Duchen, Michael R; Szabadkai, Gyorgy; Baker, David; Selwood, David L |
The Journal of Biological Chemistry |
2016 |
10.1074/jbc.M115.700385 |
325. |
Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity. |
Dott, William; Mistry, Pratibha; Wright, Jayne; Cain, Kelvin; Herbert, Karl E |
Redox biology |
2014 |
10.1016/j.redox.2013.12.028 |
326. |
Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants. |
Delp, Johannes; Funke, Melina; Rudolf, Franziska; Cediel, Andrea; Bennekou, Susanne Hougaard; van der Stel, Wanda; Carta, Giada; Jennings, Paul; Toma, Cosimo; Gardner, Iain; van de Water, Bob; Forsby, Anna; Leist, Marcel |
Archives of Toxicology |
2019 |
10.1007/s00204-019-02473-y |
327. |
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. |
Pereira, Gon?alo C; Branco, Ana F; Matos, J?lio A C; Pereira, Sandro L; Parke, Donna; Perkins, Edward L; Serafim, Teresa L; Sard?o, Vilma A; Santos, Maria S; Moreno, Antonio J M; Holy, Jon; Oliveira, Paulo J |
The Journal of Pharmacology and Experimental Therapeutics |
2007 |
10.1124/jpet.107.128017 |
328. |
Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. |
Turner, Nigel; Li, Jing-Ya; Gosby, Alison; To, Sabrina W C; Cheng, Zhe; Miyoshi, Hiroyuki; Taketo, Makoto M; Cooney, Gregory J; Kraegen, Edward W; James, David E; Hu, Li-Hong; Li, Jia; Ye, Ji-Ming |
Diabetes |
2008 |
10.2337/db07-1552 |
329. |
mTOR inhibitors in cancer therapy. |
Xie, Jianling; Wang, Xuemin; Proud, Christopher G |
F1000Research |
2016 |
10.12688/f1000research.9207.1 |
330. |
Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells. |
Bova, Michael P; Tam, Danny; McMahon, Gerald; Mattson, Matthew N |
Toxicology Letters |
2005 |
10.1016/j.toxlet.2004.08.009 |