T003
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Gentamicin | 1.94 mM | rat | isolated rat liver mitochondria | The activity of complex III was measured by following the rate of reduction of cytochrome C at 550 nm using 50 μM ubiquinol 2 in the presence of 1 mM cyanide (KCN) to prevent electron transfer to complex IV. | Positive | IC50 | 316 | |