T363 Source: Uniprot

enzymeDynamin-like 120 kDa protein, mitochondrial (Optic atrophy protein 1)
Hydrolase
Full Name Dynamin-like 120 kDa protein, mitochondrial
Protein Names Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like 120 kDa protein, form S1]
Subcellular Location Mitochondrion inner membrane Mitochondrion intermembrane space Mitochondrion membrane Single-pass membrane protein
EC numbers 3.6.5.5
Uniprot Accession O60313
Uniprot Name OPA1_HUMAN
Gene symbol OPA1
Gene Name OPA1, mitochondrial dynamin like GTPase
Ensembl ENSG00000198836

Compound Dose Time Species Model Method Result Positive criterion Reference
BGP-15 50 μM 4hr WRL-68 cells Polyethylene glycol (PEG) fusion assay; OPA1 GTPase assay and OPA1-OPA1 interactions Positive 297