Compound

D1425 | BGP-15

Molecular Formula C14H24Cl2N4O2
Molecular Weight 351.3
Structure
Description hydroxylamine derivative; PARP inhibitor and insulin sensitizer; prevents insulin resistance in humans and protects against several oxidative stress-related diseases

Toxicity Dose Time Species Model Method Action Positive criterion Reference
FRAGMENTATION 50 μM 4hr WRL-68 cells mERFP-labeled WRL-68 cells reduce 297
FUSION 50 μM 4hr WRL-68 cells Polyethylene glycol (PEG) fusion assay; OPA1 GTPase assay and OPA1-OPA1 interactions induce 297

Target Dose Time Species Model Method Action Positive criterion Reference
Dynamin-like 120 kDa protein, mitochondrial 50 μM 4hr WRL-68 cells Polyethylene glycol (PEG) fusion assay; OPA1 GTPase assay and OPA1-OPA1 interactions activate 297


  • N-[2-hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide, dihydrochloride

    CAS Number 66611-37-8
    PubChem Compound 9884807