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Compound

D0563 | venturicidin B

Molecular Formula C40H66O10
Molecular Weight 706.9
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
ELECTRON TRANSPORT CHAIN affect 170
ELECTRON TRANSPORT CHAIN 9 μg inhibitor/mg protein E. coli membrane vesicle decrease IC50 152
ELECTRON TRANSPORT CHAIN 11 μg inhibitor/mg protein E. coli membrane-bound ATPase decrease IC50 152
ELECTRON TRANSPORT CHAIN 0.13 μg inhibitor/mg protein decrease IC50 153
ELECTRON TRANSPORT CHAIN 0.06-0.18 (A and B) and 11.0 (X) μg inhibitor/mg protein S. cerevisiae SMP-ATPase decrease IC50 159
ELECTRON TRANSPORT CHAIN 5-11 μg inhibitor/mg protein T. pyriformis decrease IC50 138
ELECTRON TRANSPORT CHAIN 3.0 μg/mg protein C. asciculate SMP-ATPase decrease IC50 131
ELECTRON TRANSPORT CHAIN 0.5 μM spinach thylakoids decrease IC50 160
ELECTRON TRANSPORT CHAIN 0.5 μM spinach thylakoids, ATPase decrease IC50 160

Target Dose Time Species Model Method Action Positive criterion Reference
ATP synthase 9 μg inhibitor/mg protein E. coli membrane vesicle inhibitor IC50 152
ATP synthase 11 μg inhibitor/mg protein E. coli membrane-bound ATPase inhibitor IC50 152
ATP synthase 0.13 μg inhibitor/mg protein inhibitor IC50 153
ATP synthase 0.06-0.18 (A and B) and 11.0 (X) μg inhibitor/mg protein S. cerevisiae SMP-ATPase inhibitor IC50 159
ATP synthase 5-11 μg inhibitor/mg protein T. pyriformis inhibitor IC50 138
ATP synthase 3.0 μg/mg protein C. asciculate SMP-ATPase inhibitor IC50 131
ATP synthase 0.5 μM spinach thylakoids inhibitor IC50 160
ATP synthase 0.5 μM spinach thylakoids, ATPase inhibitor IC50 160
Fo subunits inhibitor 170


  • 33538-72-6 8S254814I6 Aabomycin A
    Q27270947 UNII-7RJ2C0030Y component VIOYQVOQUWWSAB-KEXSXYLYSA-N UNII-8S254814I6
    Venturicidin B ZINC169731029

    CAS Number 33538-72-6
    PubChem Compound 10032713
    ChEBI 83165
    ChemSpider 8208283