Drug
D1438 | Acyclovir
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| ELECTRON TRANSPORT CHAIN | Interfere | 307 | ||||||
| ULTRASTRUCTURE | abnormalize | 307 | ||||||
| ROS PRODUCTION | Increase | 307 | ||||||
| MITOCHONDRIAL DNA METABOLIC PROCESS | increase | 307 | ||||||
| MITOCHONDRIAL PROTEIN TRANSLATION | decrease | 307 | ||||||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Cytochrome c oxidase | Inhibition | 307 | ||||||
| Citrate synthase, mitochondrial | Inhibition | 307 | ||||||
| Reactive oxygen species | increase | 307 | ||||||