F022101 | GSH content
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Troglitazone | 10 µM | ZDF fa/fa rat vs ZDF lean rat | isolated mitochondria | Measurement of reduced/oxidized glutathione (GSH/GSSG): the reduced/oxidized glutathione (GSH/GSSG) concentration of the samples was determined from a standard curve using the enzymatic method and a Multiskan JX system. | lower | Positive | significantly different from ZDF lean rats (p < 0.05). | 225 | |