F022101 | GSH content

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Troglitazone 10 µM ZDF fa/fa rat vs ZDF lean rat isolated mitochondria Measurement of reduced/oxidized glutathione (GSH/GSSG): the reduced/oxidized glutathione (GSH/GSSG) concentration of the samples was determined from a standard curve using the enzymatic method and a Multiskan JX system. lower Positive significantly different from ZDF lean rats (p < 0.05). 225