F0310 | Protein-containing complex assembly
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| doxycycline | 15 µg/ml | 6 days | 143B osteosarcoma cells | BN PAGE analysis, In-gel complex I activity and western blotting | inhibitor | Positive | 285 | ||
| Chloramphenicol | 50 μg/ml | 5 days | 143B osteosarcoma cells | Blue Native Gel | inhibitor | Positive | 286 | ||
| Chloramphenicol | 50µg/mL | 4 days | complex I de novo assembly analysed by BN-PAGE | inhibitor | Positive | 287 | |||
| Saquinavir | decrease | Positive | 307 | ||||||