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F070106 | ER stress-induced


Cell death >> Apoptosis >> ER stress-induced

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Flufenamic Acid 68 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Tolfenamic Acid 50 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Mefenamic acid 61 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Meloxicam 153 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Sudoxicam 223 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Piroxicam 610 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Diflunisal 50 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Diclofenac 51 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Sulindac sulfide 53 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40
Nimesulide 8 24hr rat hepatocytes DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis induce Positive AC50 (μM) 40