ID Title Authors Journal Publication Year DOI
241. Pharmacological Modulation of Mitochondrial Ca2+ Content Regulates Sarcoplasmic Reticulum Ca2+ Release via Oxidation of the Ryanodine Receptor by Mitochondria-Derived Reactive Oxygen Species. Hamilton, Shanna; Terentyeva, Radmila; Kim, Tae Yun; Bronk, Peter; Clements, Richard T; O-Uchi, Jin; Csord?s, Gy?rgy; Choi, Bum-Rak; Terentyev, Dmitry Frontiers in physiology 1905 10.3389/fphys.2018.01831
242. Clinical effects of chemical exposures on mitochondrial function. Zolkipli-Cunningham, Zarazuela; Falk, Marni J Toxicology 2017 10.1016/j.tox.2017.07.009
243. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Du, Kuo; Farhood, Anwar; Jaeschke, Hartmut Archives of Toxicology 2017 10.1007/s00204-016-1692-0
244. N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production. EzeriFa, Daria; Takano, Yoko; Hanaoka, Kenjiro; Urano, Yasuteru; Dick, Tobias P Cell Chemical Biology 1905 10.1016/j.chembiol.2018.01.011
245. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Dixon, Scott J; Lemberg, Kathryn M; Lamprecht, Michael R; Skouta, Rachid; Zaitsev, Eleina M; Gleason, Caroline E; Patel, Darpan N; Bauer, Andras J; Cantley, Alexandra M; Yang, Wan Seok; Morrison, Barclay; Stockwell, Brent R Cell 1905 10.1016/j.cell.2012.03.042
246. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Yagoda, Nicholas; von Rechenberg, Moritz; Zaganjor, Elma; Bauer, Andras J; Yang, Wan Seok; Fridman, Daniel J; Wolpaw, Adam J; Smukste, Inese; Peltier, John M; Boniface, J Jay; Smith, Richard; Lessnick, Stephen L; Sahasrabudhe, Sudhir; Stockwell, Brent R Nature 1905 10.1038/nature05859
247. Mitochondrial fusion, fission, and mitochondrial toxicity. Meyer, Joel N; Leuthner, Tess C; Luz, Anthony L Toxicology 1905 10.1016/j.tox.2017.07.019
248. Mitochondria as a therapeutic target for common pathologies. Murphy, Michael P; Hartley, Richard C Nature Reviews. Drug Discovery 1905 10.1038/nrd.2018.174
249. Glycolysis inhibition for anticancer treatment. Pelicano, H; Martin, D S; Xu, R-H; Huang, P Oncogene 2006 10.1038/sj.onc.1209597
250. The significance of mitochondrial toxicity testing in drug development. Dykens, James A; Will, Yvonne Drug Discovery Today 2007 10.1016/j.drudis.2007.07.013
251. The toxicity of fluoroacetate and the tricarboxylic acid cycle Li?becq, Claude; Peters, Rudolph Albert Biochimica et biophysica acta 1949 10.1016/0006-3002(49)90095-5
252. New method to assess mitophagy flux by flow cytometry. Mauro-Lizcano, Marta; Esteban-Mart?nez, Lorena; Seco, Esther; Serrano-Puebla, Ana; Garcia-Ledo, Lucia; Figueiredo-Pereira, Cl?udia; Vieira, Helena L A; Boya, Patricia Autophagy 1905 10.1080/15548627.2015.1034403
253. [The mitochondrial biochemical lesion in pentachlorophenol intoxication]. Buffa, P; Azzone, G F; Carafoli, E; Muscatelo, U Bollettino della Societa Italiana di Biologia Sperimentale 1905
254. [Enzymatic research at the mitochondrial level in experimental carbon monoxide poisoning. Behavior of the cytochrome oxidases, aldolases and glutamic-oxalacetic and glutamic-pyruvic transaminases in the hepatic and renal mitochondria]. Villa, T; Andri, L; Brasca, F Folia medica. Folia medica (Naples, Italy) 1961
255. Therapeutic targeting of the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis in cancer. Stacpoole, Peter W Journal of the National Cancer Institute 1905 10.1093/jnci/djx071
256. Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells. Zhang, Wenjia; Su, Jing; Xu, Huadan; Yu, Shanshan; Liu, Yanan; Zhang, Yong; Sun, Liankun; Yue, Ying; Zhou, Xiaoli Plos One 1905 10.1371/journal.pone.0179672
257. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. O'Connor, Roddy S; Guo, Lili; Ghassemi, Saba; Snyder, Nathaniel W; Worth, Andrew J; Weng, Liwei; Kam, Yoonseok; Philipson, Benjamin; Trefely, Sophie; Nunez-Cruz, Selene; Blair, Ian A; June, Carl H; Milone, Michael C Scientific Reports 1905 10.1038/s41598-018-24676-6
258. Acetaminophen induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition Hinson, Jack A.; Reid, Angela B.; McCullough, Sandra S.; James, Laura P. Drug Metabolism Reviews 2004 10.1081/DMR-200033494
259. Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver. Zhao, Ping; Kalhorn, Thomas F; Slattery, John T Hepatology 2002 10.1053/jhep.2002.34943
260. Novel small-molecule PGC-1alpha transcriptional regulator with beneficial effects on diabetic db/db mice. Zhang, Li-Na; Zhou, Hua-Yong; Fu, Yan-Yun; Li, Yuan-Yuan; Wu, Fang; Gu, Min; Wu, Ling-Yan; Xia, Chun-Mei; Dong, Tian-Cheng; Li, Jing-Ya; Shen, Jing-Kang; Li, Jia Diabetes 2013 10.2337/db12-0703
261. Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease. Miyamoto, Satoshi; Zhang, Guanshi; Hall, David; Oates, Peter J; Maity, Soumya; Madesh, Muniswamy; Han, Xianlin; Sharma, Kumar The Journal of Biological Chemistry 2020 10.1074/jbc.RA119.011110
262. Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells. Fujie, Yujiro; Yamamoto, Hirofumi; Ngan, Chew Yee; Takagi, Akimitsu; Hayashi, Taro; Suzuki, Rei; Ezumi, Koji; Takemasa, Ichiro; Ikeda, Masataka; Sekimoto, Mitsugu; Matsuura, Nariaki; Monden, Morito Japanese journal of clinical oncology 2005 10.1093/jjco/hyi130
263. Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 cells. Rayamajhi, Nabin; Kim, Seul-Ki; Go, Hiroe; Joe, Yeonsoo; Callaway, Zak; Kang, Jae-Gu; Ryter, Stefan W; Chung, Hun Taeg Oxidative medicine and cellular longevity 1905 10.1155/2013/154279
264. Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors Zhang, Gao; Frederick, Dennie T.; Wu, Lawrence; Wei, Zhi; Krepler, Clemens; Srinivasan, Satish; Chae, Young Chan; Xu, Xiaowei; Choi, Harry; Dimwamwa, Elaida; Ope, Omotayo; Shannan, Batool; Basu, Devraj; Zhang, Dongmei; Guha, Manti; Xiao, Min; Randell, Sergio; Sproesser, Katrin; Xu, Wei; Liu, Jephrey; Karakousis, Giorgos C.; Schuchter, Lynn M.; Gangadhar, Tara C.; Amaravadi, Ravi K.; Gu, Mengnan; Xu, Caiyue; Ghosh, Abheek; Xu, Weiting; Tian, Tian; Zhang, Jie; Zha, Shijie; Liu, Qin; Brafford, Patricia; Weeraratna, Ashani; Davies, Michael A.; Wargo, Jennifer A.; Avadhani, Narayan G.; Lu, Yiling; Mills, Gordon B.; Altieri, Dario C.; Flaherty, Keith T.; Herlyn, Meenhard The Journal of Clinical Investigation 2016
265. Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1? Signaling Pathways. Gureev, Artem P; Shaforostova, Ekaterina A; Popov, Vasily N Frontiers in genetics 1905 10.3389/fgene.2019.00435
266. Mechanistic target of rapamycin inhibitors: successes and challenges as cancer therapeutics N? Bhaoighill, Muireann; Dunlop, Elaine A. Cancer Drug Resistance 1905 10.20517/cdr.2019.87
267. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Lagouge, Marie; Argmann, Carmen; Gerhart-Hines, Zachary; Meziane, Hamid; Lerin, Carles; Daussin, Frederic; Messadeq, Nadia; Milne, Jill; Lambert, Philip; Elliott, Peter; Geny, Bernard; Laakso, Markku; Puigserver, Pere; Auwerx, Johan Cell 1905 10.1016/j.cell.2006.11.013
268. Drug repurposing for mitochondrial diseases using a pharmacological model of complex I deficiency in the yeast Yarrowia lipolytica Perlstein, Ethan Oren BioRxiv 2020 10.1101/2020.01.08.899666
269. High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons. Varkuti, Boglarka H; Liu, Ze; Kepiro, Miklos; Pacifico, Rodrigo; Gai, Yunchao; Kamenecka, Ted; Davis, Ronald L iScience 1905 10.1016/j.isci.2020.100931
270. A molecular mechanism for mimosine-induced apoptosis involving oxidative stress and mitochondrial activation. Hallak, Maher; Vazana, Liat; Shpilberg, Ofer; Levy, Itai; Mazar, Julia; Nathan, Ilana Apoptosis: An International Journal on Programmed Cell Death 2008 10.1007/s10495-007-0156-7