ID Title Authors Journal Publication Year DOI
231. The molecular mechanism of transport by the mitochondrial ADP/ATP carrier. Ruprecht, Jonathan J; King, Martin S; Z?gg, Thomas; Aleksandrova, Antoniya A; Pardon, Els; Crichton, Paul G; Steyaert, Jan; Kunji, Edmund R S Cell 2019 10.1016/j.cell.2018.11.025
171. The oligomycin-sensitivity conferring protein of mitochondrial ATP synthase: emerging new roles in mitochondrial pathophysiology. Antoniel, Manuela; Giorgio, Valentina; Fogolari, Federico; Glick, Gary D; Bernardi, Paolo; Lippe, Giovanna International Journal of Molecular Sciences 2014 10.3390/ijms15057513
110. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I. Gassner, B; Wüthrich, A; Scholtysik, G; Solioz, M The Journal of Pharmacology and Experimental Therapeutics 1997
156. The relationship between the bovine heart mitochondrial adenosine triphosphatase, lipophilic compounds, and oligomycin. Cunningham, C C; George, D T The Journal of Biological Chemistry 1975
212. The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem. Tune, B M; Hsu, C Y Journal of the American Society of Nephrology 1990
250. The significance of mitochondrial toxicity testing in drug development. Dykens, James A; Will, Yvonne Drug Discovery Today 2007 10.1016/j.drudis.2007.07.013
280. The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-Cyano-4-hydroxycinnamate and related compounds. Halestrap, A P; Denton, R M The Biochemical Journal 1975 10.1042/bj1480097
106. The specificity of mitochondrial complex I for ubiquinones. Degli Esposti, M; Ngo, A; McMullen, G L; Ghelli, A; Sparla, F; Benelli, B; Ratta, M; Linnane, A W The Biochemical Journal 1996 10.1042/bj3130327
251. The toxicity of fluoroacetate and the tricarboxylic acid cycle Li?becq, Claude; Peters, Rudolph Albert Biochimica et biophysica acta 1949 10.1016/0006-3002(49)90095-5
178. The toxicity of fluoroacetate and the tricarboxylic acid cycle. 1949. Li?becq, C; Peters, R A Biochimica et Biophysica Acta 1905
12. The uncoupling effect of the nonsteroidal anti-inflammatory drug nimesulide in liver mitochondria from adjuvant-induced arthritic rats. Caparroz-Assef, S M; Salgueiro-Pagadigorria, C L; Bersani-Amado, C A; Bracht, A; Kelmer-Bracht, A M; Ishii-Iwamoto, E L Cell Biochemistry and Function 2001 10.1002/cbf.904
33. Thenoyltrifluoroacetone, a potent inhibitor of carboxylesterase activity. Zhang, Jin Gang; Fariss, Marc W Biochemical Pharmacology 2002 10.1016/s0006-2952(01)00871-1
322. Therapeutic potential of coenzyme Q10 in mitochondrial dysfunction during tacrolimus-induced beta cell injury. Luo, Kang; Yu, Ji Hyun; Quan, Yi; Shin, Yoo Jin; Lee, Kyung Eun; Kim, Hong Lim; Ko, Eun Jeong; Chung, Byung Ha; Lim, Sun Woo; Yang, Chul Woo Scientific Reports 2019 10.1038/s41598-019-44475-x
255. Therapeutic targeting of the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis in cancer. Stacpoole, Peter W Journal of the National Cancer Institute 1905 10.1093/jnci/djx071
34. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Divakaruni, Ajit S; Wiley, Sandra E; Rogers, George W; Andreyev, Alexander Y; Petrosyan, Susanna; Loviscach, Mattias; Wall, Estelle A; Yadava, Nagendra; Heuck, Alejandro P; Ferrick, David A; Henry, Robert R; McDonald, William G; Colca, Jerry R; Simon, Melvin I; Ciaraldi, Theodore P; Murphy, Anne N Proceedings of the National Academy of Sciences of the United States of America 2013 10.1073/pnas.1303360110
112. Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. Andreani, A; Rambaldi, M; Leoni, A; Locatelli, A; Ghelli, A; Ratta, M; Benelli, B; Degli Esposti, M Journal of Medicinal Chemistry 1995 10.1021/jm00007a006
73. Thiophene carboxamide fungicides: Structure-activity relationships with the succinate dehydrogenase complex from wild-type and carboxin-resistant mutant strains of Ustilago maydis White, G.A.; Thorn, G.D. Pesticide biochemistry and physiology 1980 10.1016/0048-3575(80)90020-6
237. Tianeptine, a new tricyclic antidepressant metabolized by beta-oxidation of its heptanoic side chain, inhibits the mitochondrial oxidation of medium and short chain fatty acids in mice. Fromenty, B; Freneaux, E; Labbe, G; Deschamps, D; Larrey, D; Letteron, P; Pessayre, D Biochemical Pharmacology 1989 10.1016/0006-2952(89)90580-7
305. Toxicity and Loss of Mitochondrial Membrane Potential Induced by Alkyl Gallates in Trypanosoma cruzi. Andr?o, Rog?rio; Regasini, Lu?s Oct?vio; Petr?nio, Maicon Segalla; Chiari-Andr?o, Bruna Galdorfini; Tansini, Aline; Silva, Dulce Helena Siqueira; Cicarelli, Regina Maria Barretto International scholarly research notices 2015 10.1155/2015/924670
40. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Nadanaciva, Sashi; Aleo, Michael D; Strock, Christopher J; Stedman, Donald B; Wang, Huijun; Will, Yvonne Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.06.019
93. Tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio) embryos/larvae at environmentally relevant levels. Liang, Xuefang; Souders, Christopher L; Zhang, Jiliang; Martyniuk, Christopher J Chemosphere 2017 10.1016/j.chemosphere.2017.09.093
89. Triclosan is a mitochondrial uncoupler in live zebrafish. Shim, Juyoung; Weatherly, Lisa M; Luc, Richard H; Dorman, Maxwell T; Neilson, Andy; Ng, Ryan; Kim, Carol H; Millard, Paul J; Gosse, Julie A Journal of Applied Toxicology 2016 10.1002/jat.3311
330. Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells. Bova, Michael P; Tam, Danny; McMahon, Gerald; Mattson, Matthew N Toxicology Letters 2005 10.1016/j.toxlet.2004.08.009
226. Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes. Rachek, Lyudmila I; Yuzefovych, Larysa V; Ledoux, Susan P; Julie, Neil L; Wilson, Glenn L Toxicology and Applied Pharmacology 2009 10.1016/j.taap.2009.07.021
94. Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich, T; van Heek, P; Leif, H; Ohnishi, T; Forche, E; Kunze, B; Jansen, R; Trowitzsch-Kienast, W; Höfle, G; Reichenbach, H European Journal of Biochemistry / FEBS 1994 10.1111/j.1432-1033.1994.tb19985.x
133. Uncoupling and specific inhibition of phosphoryl transfer reactions in mitochondria by antibiotic A20668. Reed, P W; Lardy, H A The Journal of Biological Chemistry 1975
221. Uncoupling of Oxidative Phosphorylation by Carbonyl Cyanide Phenylhydrazones. I. Some Characteristics of m-CI-CCP Action on Mitochondria and Chloroplasts Heytler, P. G. Biochemistry 1963 10.1021/bi00902a031
210. Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat. Somasundaram, S; Sigthorsson, G; Simpson, R J; Watts, J; Jacob, M; Tavares, I A; Rafi, S; Roseth, A; Foster, R; Price, A B; Wrigglesworth, J M; Bjarnason, I Alimentary Pharmacology & Therapeutics 2000 10.1046/j.1365-2036.2000.00723.x
184. Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F(0)F(1)-ATPase. Salomon, A R; Voehringer, D W; Herzenberg, L A; Khosla, C Proceedings of the National Academy of Sciences of the United States of America 1905 10.1073/pnas.97.26.14766
154. Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F(0)F(1)-ATPase. Salomon, A R; Voehringer, D W; Herzenberg, L A; Khosla, C Proceedings of the National Academy of Sciences of the United States of America 2000 10.1073/pnas.97.26.14766