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34. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Divakaruni, Ajit S; Wiley, Sandra E; Rogers, George W; Andreyev, Alexander Y; Petrosyan, Susanna; Loviscach, Mattias; Wall, Estelle A; Yadava, Nagendra; Heuck, Alejandro P; Ferrick, David A; Henry, Robert R; McDonald, William G; Colca, Jerry R; Simon, Melvin I; Ciaraldi, Theodore P; Murphy, Anne N Proceedings of the National Academy of Sciences of the United States of America 2013 10.1073/pnas.1303360110
245. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Dixon, Scott J; Lemberg, Kathryn M; Lamprecht, Michael R; Skouta, Rachid; Zaitsev, Eleina M; Gleason, Caroline E; Patel, Darpan N; Bauer, Andras J; Cantley, Alexandra M; Yang, Wan Seok; Morrison, Barclay; Stockwell, Brent R Cell 1905 10.1016/j.cell.2012.03.042
325. Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity. Dott, William; Mistry, Pratibha; Wright, Jayne; Cain, Kelvin; Herbert, Karl E Redox biology 2014 10.1016/j.redox.2013.12.028
191. Inhibition of mitochondrial ATPase by dicarbopolyborate, a new enzyme inhibitor. Drahota, Z; Mares, V; Rauchov?, H; Saf, P; Kalous, M Journal of Bioenergetics and Biomembranes 1994 10.1007/BF00762743
243. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Du, Kuo; Farhood, Anwar; Jaeschke, Hartmut Archives of Toxicology 2017 10.1007/s00204-016-1692-0
174. In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone. Dykens, James A; Jamieson, Joseph D; Marroquin, Lisa D; Nadanaciva, Sashi; Xu, Jinghai J; Dunn, Margaret C; Smith, Arthur R; Will, Yvonne Toxicological Sciences 2008 10.1093/toxsci/kfn056
15. Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. Dykens, James A; Jamieson, Joseph; Marroquin, Lisa; Nadanaciva, Sashi; Billis, Puja A; Will, Yvonne Toxicology and Applied Pharmacology 2008 10.1016/j.taap.2008.08.013
175. Strategies to reduce late-stage drug attrition due to mitochondrial toxicity. Dykens, James A; Marroquin, Lisa D; Will, Yvonne Expert Review of Molecular Diagnostics 2014 10.1586/14737159.7.2.161
250. The significance of mitochondrial toxicity testing in drug development. Dykens, James A; Will, Yvonne Drug Discovery Today 2007 10.1016/j.drudis.2007.07.013
35. A combined in vitro approach to improve the prediction of mitochondrial toxicants. Eakins, Julie; Bauch, Caroline; Woodhouse, Heather; Park, Benjamin; Bevan, Samantha; Dilworth, Clive; Walker, Paul Toxicology in Vitro 2016 10.1016/j.tiv.2016.03.016
155. Nuclear mutations conferring oligomycin resistance in Neurospora crassa. Edwards, D L; Unger, B W The Journal of Biological Chemistry 1978
213. Bioenergetic disruption of human micro-vascular endothelial cells by antipsychotics. Elmorsy, Ekramy; Smith, Paul A Biochemical and Biophysical Research Communications 2015 10.1016/j.bbrc.2015.03.122
101. Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. II. Physico-chemical properties and structure elucidation. Engler, M; Anke, T; Sterner, O The Journal of Antibiotics 1997 10.7164/antibiotics.50.330
224. Mitochondrial dysfunction caused by drugs and environmental toxicants Enoch, Steve; Mellor, Claire; Nelms, Mark 2018 10.1002/9781119329725.ch3
167. Inhibitors of cytochrome c oxidase Erecińska, Maria; Wilson, David F. Pharmacology & Therapeutics 1980 10.1016/0163-7258(80)90057-1
83. Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. Esser, Lothar; Quinn, Byron; Li, Yong-Fu; Zhang, Minquan; Elberry, Maria; Yu, Linda; Yu, Chang-An; Xia, Di Journal of Molecular Biology 2004 10.1016/j.jmb.2004.05.065
182. Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. Esser, Lothar; Quinn, Byron; Li, Yong-Fu; Zhang, Minquan; Elberry, Maria; Yu, Linda; Yu, Chang-An; Xia, Di Journal of Molecular Biology 1905 10.1016/j.jmb.2004.05.065
315. Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death. Esterberg, Robert; Linbo, Tor; Pickett, Sarah B; Wu, Patricia; Ou, Henry C; Rubel, Edwin W; Raible, David W The Journal of Clinical Investigation 2016 10.1172/JCI84939
22. Effect of tricyclic drugs on mitochondrial membrane. Eto, K; Fukuda, T; Araki, Y; Inoue, B; Ogata, M Acta medica Okayama 1985 10.18926/AMO/31500
244. N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production. EzeriFa, Daria; Takano, Yoko; Hanaoka, Kenjiro; Urano, Yasuteru; Dick, Tobias P Cell Chemical Biology 1905 10.1016/j.chembiol.2018.01.011
271. Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone. Felser, Andrea; Blum, Kim; Lindinger, Peter W; Bouitbir, Jamal; Kr?henb?hl, Stephan Toxicological Sciences 2012 10.1093/toxsci/kfs298
37. Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Felser, Andrea; Lindinger, Peter W; Schnell, Dominik; Kratschmar, Denise V; Odermatt, Alex; Mies, Suzette; Jenö, Paul; Krähenbühl, Stephan Toxicology 2014 10.1016/j.tox.2014.08.002
311. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Filichia, Emily; Hoffer, Barry; Qi, Xin; Luo, Yu Scientific Reports 2016 10.1038/srep32656
113. Pethidine analogues, a novel class of potent inhibitors of mitochondrial NADH: ubiquinone reductase. Filser, M; Werner, S Biochemical Pharmacology 1988 10.1016/0006-2952(88)90245-6
130. Studies on the proton-translocating NADH:ubiquinone oxidoreductases of mitochondria and Escherichia coli using the inhibitor 1,10-phenanthroline. Finel, M; Majander, A FEBS Letters 1994 10.1016/0014-5793(94)80402-8
230. Phosphate carrier of liver mitochondria: the reaction of its SH groups with mersalyl, 5,5'-dithio-bis-nitrobenzoate, and N-ethylmaleimide and the modulation of reactivity by the energy state of the mitochondria. Fonyo, A; Vignais, P V Journal of Bioenergetics and Biomembranes 1980 10.1007/BF00744679
287. Dissecting the roles of mitochondrial complex I intermediate assembly complex factors in the biogenesis of complex I. Formosa, Luke E; Muellner-Wong, Linden; Reljic, Boris; Sharpe, Alice J; Jackson, Thomas D; Beilharz, Traude H; Stojanovski, Diana; Lazarou, Michael; Stroud, David A; Ryan, Michael T Cell reports 2020 10.1016/j.celrep.2020.107541
236. Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: possible role in microvesicular steatosis induced by this antibiotic. Fr?neaux, E; Labbe, G; Letteron, P; The Le Dinh, ; Degott, C; Gen?ve, J; Larrey, D; Pessayre, D Hepatology 1988 10.1002/hep.1840080513
88. Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway. Fraher, Daniel; Ellis, Megan K; Morrison, Shona; McGee, Sean L; Ward, Alister C; Walder, Ken; Gibert, Yann Endocrinology 2015 10.1210/EN.2015-1315
239. Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids. Freneaux, E; Fromenty, B; Berson, A; Labbe, G; Degott, C; Letteron, P; Larrey, D; Pessayre, D The Journal of Pharmacology and Experimental Therapeutics 1990