ID Title Authors Journal Publication Year DOI
17. Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. Lee, Leong; Horowitz, John; Frenneaux, Michael European Heart Journal 2004 10.1016/j.ehj.2004.02.018
163. Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies. Xia, Menghang; Huang, Ruili; Shi, Qiang; Boyd, Windy A; Zhao, Jinghua; Sun, Nuo; Rice, Julie R; Dunlap, Paul E; Hackstadt, Amber J; Bridge, Matt F; Smith, Marjolein V; Dai, Sheng; Zheng, Wei; Chu, Pei-Hsuan; Gerhold, David; Witt, Kristine L; DeVito, Michael; Freedman, Jonathan H; Austin, Christopher P; Houck, Keith A; Thomas, Russell S; Paules, Richard S; Tice, Raymond R; Simeonov, Anton Environmental Health Perspectives 2018 10.1289/EHP2589
88. Lipid abundance in zebrafish embryos is regulated by complementary actions of the endocannabinoid system and retinoic acid pathway. Fraher, Daniel; Ellis, Megan K; Morrison, Shona; McGee, Sean L; Ward, Alister C; Walder, Ken; Gibert, Yann Endocrinology 2015 10.1210/EN.2015-1315
258. Acetaminophen induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition Hinson, Jack A.; Reid, Angela B.; McCullough, Sandra S.; James, Laura P. Drug Metabolism Reviews 2004 10.1081/DMR-200033494
250. The significance of mitochondrial toxicity testing in drug development. Dykens, James A; Will, Yvonne Drug Discovery Today 2007 10.1016/j.drudis.2007.07.013
90. The cellular and molecular progression of mitochondrial dysfunction induced by 2,4-dinitrophenol in developing zebrafish embryos. Bestman, Jennifer E; Stackley, Krista D; Rahn, Jennifer J; Williamson, Tucker J; Chan, Sherine S L Differentiation; Research in Biological Diversity 2015 10.1016/j.diff.2015.01.001
328. Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Turner, Nigel; Li, Jing-Ya; Gosby, Alison; To, Sabrina W C; Cheng, Zhe; Miyoshi, Hiroyuki; Taketo, Makoto M; Cooney, Gregory J; Kraegen, Edward W; James, David E; Hu, Li-Hong; Li, Jia; Ye, Ji-Ming Diabetes 2008 10.2337/db07-1552
260. Novel small-molecule PGC-1alpha transcriptional regulator with beneficial effects on diabetic db/db mice. Zhang, Li-Na; Zhou, Hua-Yong; Fu, Yan-Yun; Li, Yuan-Yuan; Wu, Fang; Gu, Min; Wu, Ling-Yan; Xia, Chun-Mei; Dong, Tian-Cheng; Li, Jing-Ya; Shen, Jing-Kang; Li, Jia Diabetes 2013 10.2337/db12-0703
177. Current concepts in drug-induced mitochondrial toxicity. Nadanaciva, Sashi; Will, Yvonne Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2009 10.1002/0471140856.tx0215s40
227. Drug-Induced Inhibition of Mitochondrial Fatty Acid Oxidation and Steatosis Massart, Julie; Begriche, Karima; Buron, Nelly; Porceddu, Mathieu; Borgne-Sanchez, Annie; Fromenty, Bernard Current pathobiology reports 2013 10.1007/s40139-013-0022-y
278. Multiple Targets for Drug-Induced Mitochondrial Toxicity. Wallace, Kendall B Current Medicinal Chemistry 1905 10.2174/0929867322666150514095424
41. Bioactivation and hepatotoxicity of nitroaromatic drugs. Boelsterli, Urs A; Ho, Han Kiat; Zhou, Shufeng; Leow, Koon Yeow Current Drug Metabolism 2006 10.2174/138920006778520606
71. Progress in understanding molecular mechanisms and evolution of resistance to succinate dehydrogenase inhibiting (SDHI) fungicides in phytopathogenic fungi Avenot, Hervé F.; Michailides, Themis J. Crop Protection 2010 10.1016/j.cropro.2010.02.019
85. A bioenergetics assay for studying the effects of environmental stressors on mitochondrial function in vivo in zebrafish larvae. Raftery, Tara D; Jayasundara, Nishad; Di Giulio, Richard T Comparative Biochemistry and Physiology. Toxicology & Pharmacology 2017 10.1016/j.cbpc.2016.12.001
65. Effects of indomethacin on energy metabolism in rat and human jejunal tissue in vitro. Jacob, M; Bjarnason, I; Simpson, R J Clinical Science 2001 10.1042/cs1010493
188. Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells. Akao, M; Ohler, A; O'Rourke, B; Marb?n, E Circulation Research 2001 10.1161/hh1201.092094
93. Tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio) embryos/larvae at environmentally relevant levels. Liang, Xuefang; Souders, Christopher L; Zhang, Jiliang; Martyniuk, Christopher J Chemosphere 2017 10.1016/j.chemosphere.2017.09.093
26. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Ma, Xiuquan; Jin, Mingzhi; Cai, Yu; Xia, Hongguang; Long, Kai; Liu, Junli; Yu, Qiang; Yuan, Junying Chemistry & Biology 2011 10.1016/j.chembiol.2011.08.009
53. Evaluation of in vitro mitochondrial toxicity assays and physicochemical properties for prediction of organ toxicity using 228 pharmaceutical drugs. Rana, Payal; Aleo, Michael D; Gosink, Mark; Will, Yvonne Chemical Research in Toxicology 2019 10.1021/acs.chemrestox.8b00246
223. Development of an in silico profiler for mitochondrial toxicity Nelms, Mark D; Mellor, Claire L; Cronin, Mark T D; Madden, Judith C; Enoch, Steven J Chemical Research in Toxicology 2015 10.1021/acs.chemrestox.5b00275
218. ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak. Debattisti, Valentina; Gerencser, Akos A; Saotome, Masao; Das, Sudipto; Hajn?czky, Gy?rgy Cell reports 2017 10.1016/j.celrep.2017.10.060
301. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Di Marco, Giulia; Vallese, Francesca; Jourde, Benjamin; Bergsdorf, Christian; Sturlese, Mattia; De Mario, Agnese; Techer-Etienne, Valerie; Haasen, Dorothea; Oberhauser, Berndt; Schleeger, Simone; Minetti, Giulia; Moro, Stefano; Rizzuto, Rosario; De Stefani, Diego; Fornaro, Mara; Mammucari, Cristina Cell reports 2020 10.1016/j.celrep.2020.01.081
287. Dissecting the roles of mitochondrial complex I intermediate assembly complex factors in the biogenesis of complex I. Formosa, Luke E; Muellner-Wong, Linden; Reljic, Boris; Sharpe, Alice J; Jackson, Thomas D; Beilharz, Traude H; Stojanovski, Diana; Lazarou, Michael; Stroud, David A; Ryan, Michael T Cell reports 2020 10.1016/j.celrep.2020.107541
302. DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter. Kon, Naohiro; Murakoshi, Michiko; Isobe, Aya; Kagechika, Katsuji; Miyoshi, Naoki; Nagayama, Takahiro Cell death discovery 2017 10.1038/cddiscovery.2017.45
46. Effects of tamoxifen on the electron transport chain of isolated rat liver mitochondria. Tuquet, C; Dupont, J; Mesneau, A; Roussaux, J Cell biology and toxicology 1905 10.1023/a:1007695308257
286. The assembly pathway of mitochondrial respiratory chain complex I. Guerrero-Castillo, Sergio; Baertling, Fabian; Kownatzki, Daniel; Wessels, Hans J; Arnold, Susanne; Brandt, Ulrich; Nijtmans, Leo Cell Metabolism 2017 10.1016/j.cmet.2016.09.002
180. Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition. Schirris, Tom J J; Renkema, G Herma; Ritschel, Tina; Voermans, Nicol C; Bilos, Albert; van Engelen, Baziel G M; Brandt, Ulrich; Koopman, Werner J H; Beyrath, Julien D; Rodenburg, Richard J; Willems, Peter H G M; Smeitink, Jan A M; Russel, Frans G M Cell Metabolism 2015 10.1016/j.cmet.2015.08.002
276. Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency. Son, M J; Kwon, Y; Son, M-Y; Seol, B; Choi, H-S; Ryu, S-W; Choi, C; Cho, Y S Cell Death and Differentiation 2015 10.1038/cdd.2015.43
295. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism. Miret-Casals, Laia; Sebasti?n, David; Brea, Jos?; Rico-Leo, Eva M; Palac?n, Manuel; Fern?ndez-Salguero, Pedro M; Loza, M Isabel; Albericio, Fernando; Zorzano, Antonio Cell Chemical Biology 1905 10.1016/j.chembiol.2017.12.001
320. Selective disruption of mitochondrial thiol redox state in cells and in?vivo. Booty, Lee M; Gawel, Justyna M; Cvetko, Filip; Caldwell, Stuart T; Hall, Andrew R; Mulvey, John F; James, Andrew M; Hinchy, Elizabeth C; Prime, Tracy A; Arndt, Sabine; Beninca, Cristiane; Bright, Thomas P; Clatworthy, Menna R; Ferdinand, John R; Prag, Hiran A; Logan, Angela; Prudent, Julien; Krieg, Thomas; Hartley, Richard C; Murphy, Michael P Cell Chemical Biology 2019 10.1016/j.chembiol.2018.12.002