N,N'-dicyclohexylcarbodiimide |
1 mol inhibitor/mol F0 |
|
E. coli |
membrane H+-translocation |
|
Positive |
maximal inhibition |
170 |
woodward's reagent k |
|
|
|
|
|
Positive |
|
170 |
Mersalyl |
130 μM |
|
bovine |
heart MF0, proton conductivity |
|
Positive |
70% inhibition |
170 |
Oligomycin |
152 μg inhibitor/mg protein |
|
E. coli |
membrane vesicle, pH gradient formation |
|
Positive |
|
170 |
Oligomycin |
7.1 μg inhibitor/mg protein |
|
C. asciculate |
SMP-ATPase |
|
Positive |
IC50 |
170 |
Oligomycin |
2.0-3.0 μg inhibitor/mg protein |
|
S. cerevisiae |
SMP-ATPase |
|
Positive |
IC50 |
170 |
Oligomycin |
0.3 μM |
|
human NCI-60 cell lines |
F0F1-ATPase |
|
Positive |
IC50 |
170 |
Oligomycin |
15 ng inhibitor/mg protein |
|
N. crassa |
SMP-ATPase |
|
Positive |
Ki |
170 |
Oligomycin |
0.21 μM |
|
bovine |
heart MF0F1-ATPase |
|
Positive |
Ki |
170 |
Oligomycin |
0.4 μg inhibitor/mg protein |
|
bovine |
heart SMP-ATPase |
|
Positive |
95% inhibition |
170 |
Oligomycin |
0.5 μg/ml |
|
rat |
liver SMP-ATPase |
|
Positive |
75% inhibition |
170 |
ossamycin |
46 μg of inhibitor/mg protein |
|
E. coli |
pH gradient formation by membrane vesicle |
|
Positive |
IC50 |
170 |
ossamycin |
8 μM |
|
human NCI-60 cell lines |
F0F1-ATPase |
|
Positive |
IC50 |
170 |
ossamycin |
1.3 μg of inhibitor/mg protein |
|
S. cerevisiae |
SMP-ATPase |
|
Positive |
IC50 |
170 |
venturicidin B |
|
|
|
|
|
Positive |
|
170 |
Bedaquiline |
|
|
|
|
|
Positive |
|
170 |
NCCD |
0.65 nmol/mg protein |
|
bovine |
heart SMP-ATPase |
|
Positive |
IC50 |
170 |
NCCD |
1 nmol NCCD/mg protein |
|
bovine |
heart SMP-ATPase |
|
Positive |
85% inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
0.2 μg of inhibitor/mg protein |
|
S. cerevisiae |
SMP-ATPase |
|
Positive |
IC50 |
170 |
N,N'-dicyclohexylcarbodiimide |
1-5 μg of inhibitor/mg protein |
|
T. pyriformis |
SMP-ATPase |
|
Positive |
IC50 |
170 |
N,N'-dicyclohexylcarbodiimide |
200 μMa in less than 5 min and at ∼40 μMa in 30 min |
|
R. rubrum |
F1-ATPase |
|
Positive |
|
170 |
N,N'-dicyclohexylcarbodiimide |
1.9 μg/mg protein |
|
C. fasciculata |
SMP-ATPase |
|
Positive |
IC50 |
170 |
N,N'-dicyclohexylcarbodiimide |
1 mol DCCD/mol F1 |
|
|
EF1-ATPase |
|
Positive |
95% inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
30 μM |
|
|
membrane-bound EF0F1-ATPase |
|
Positive |
maximal 70-80% inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
5 μM |
|
C. thermoaceticum |
membrane-bound F0F1-ATPase |
|
Positive |
47% inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
2 mol inhibitor bound/mol F1 |
|
bovine |
heart MF1-ATPase |
|
Positive |
97% inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
1 mol inhibitor/mol F0 |
|
bovine |
heart SMP-ATPase |
|
Positive |
maximal inhibition |
170 |
N,N'-dicyclohexylcarbodiimide |
2 mol inhibitor/mol F0 |
|
bovine |
heart H+-translocation |
|
Positive |
maximal inhibition |
170 |