T080001 Source: Uniprot

enzyme[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1) (PDK1)
Transferase Kinase
Pyruvate dehydrogenase kinase >>
Full Name [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
Protein Names [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
Subcellular Location Mitochondrion matrix
EC numbers 2.7.11.2
Uniprot Accession Q15118
Uniprot Name PDK1_HUMAN
Gene symbol PDK1
Gene Name Pyruvate dehydrogenase kinase 1
Ensembl ENSG00000152256

Compound Dose Time Species Model Method Result Positive criterion Reference
AZD7545 Positive 256
VER-246608 Positive 256
JX06 Positive 256
radicicol Positive 256
AZD7545 Positive IC50 255
Dicoumarol 19.42 μM ovarian cancer cell line SKOV3 Positive IC50 256